EDITORIAL:

Bert Brunekreef

A Tale of Six Cities

Am. J. Respir. Crit. Care Med. 2006; 173: 581-582 [Full Text] [PDF]  

OCCASIONAL ESSAY:

John B. West

How Well Designed Is the Human Lung?

Am. J. Respir. Crit. Care Med. 2006; 173: 583-584. First published online December 30 2005 as doi:10.1164/rccm.200510-1682OE [Full Text] [PDF]  

PULMONARY AND CRITICAL CARE UPDATES:

Andrew Bush

Update in Pediatrics 2005

Am. J. Respir. Crit. Care Med. 2006; 173: 585-592 [Full Text] [PDF]  

Marc Estenne and Robert M. Kotloff

Update in Transplantation 2005

Am. J. Respir. Crit. Care Med. 2006; 173: 593-598 [Full Text] [PDF]  

ARTICLES:

A. Asthma and Allergy:

Peter Ettmayer, Peter Mayer, Frank Kalthoff, Wolfgang Neruda, Nathalie Harrer, Gabriella Hartmann, Michelle M. Epstein, Volker Brinkmann, Christoph Heusser, and Maximilian Woisetschläger

A Novel Low Molecular Weight Inhibitor of Dendritic Cells and B Cells Blocks Allergic Inflammation

Am. J. Respir. Crit. Care Med. 2006; 173: 599-606. First published online December 30 2005 as doi:10.1164/rccm.200503-468OC [Abstract] [Full Text] [PDF]  

Elena Goleva, Ling-bo Li, P. Taylor Eves, Matthew J. Strand, Richard J. Martin, and Donald Y. M. Leung

Increased Glucocorticoid Receptor Alters Steroid Response in Glucocorticoid-insensitive Asthma

Am. J. Respir. Crit. Care Med. 2006; 173: 607-616. First published online December 30 2005 as doi:10.1164/rccm.200507-1046OC [Abstract] [Full Text] [PDF]  

Andrew C. Martin, Ingrid A. Laing, Siew-Kim Khoo, Guicheng Zhang, Kristina Rueter, Laurel Teoh, Shahir Taheri, Catherine M. Hayden, Gary C. Geelhoed, Jack Goldblatt, and Peter N. LeSouëf

Acute Asthma in Children: Relationships among CD14 and CC16 Genotypes, Plasma Levels, and Severity

Am. J. Respir. Crit. Care Med. 2006; 173: 617-622. First published online December 30 2005 as doi:10.1164/rccm.200509-1367OC [Abstract] [Full Text] [PDF] [Online Supplement]  

B. Chronic Obstructive Pulmonary Disease:

Robert F. Foronjy, Oleg Mirochnitchenko, Olga Propokenko, Vincent Lemaitre, Yuxia Jia, Masayori Inouye, Yasunori Okada, and Jeanine M. D'Armiento

Superoxide Dismutase Expression Attenuates Cigarette Smoke– or Elastase-generated Emphysema in Mice

Am. J. Respir. Crit. Care Med. 2006; 173: 623-631. First published online December 30 2005 as doi:10.1164/rccm.200506-850OC [Abstract] [Full Text] [PDF] [Online Supplement]  

Faye E. Sirianni, Alireza Milaninezhad, Fanny S. F. Chu, and David C. Walker

Alteration of Fibroblast Architecture and Loss of Basal Lamina Apertures in Human Emphysematous Lung

Am. J. Respir. Crit. Care Med. 2006; 173: 632-638. First published online January 13 2006 as doi:10.1164/rccm.200509-1434OC [Abstract] [Full Text] [PDF]  

Ann R. Falsey, Maria A. Formica, Patricia A. Hennessey, Mary M. Criddle, Wayne M. Sullender, and Edward E. Walsh

Detection of Respiratory Syncytial Virus in Adults with Chronic Obstructive Pulmonary Disease

Am. J. Respir. Crit. Care Med. 2006; 173: 639-643. First published online December 30 2005 as doi:10.1164/rccm.200510-1681OC [Abstract] [Full Text] [PDF]  

C. Critical Care:

Alix Ashare, Martha M. Monick, Linda S. Powers, Timur Yarovinsky, and Gary W. Hunninghake

Severe Bacteremia Results in a Loss of Hepatic Bacterial Clearance

Am. J. Respir. Crit. Care Med. 2006; 173: 644-652. First published online January 6 2006 as doi:10.1164/rccm.200509-1470OC [Abstract] [Full Text] [PDF]  

Sina A. Gharib, W. Conrad Liles, Gustavo Matute-Bello, Robb W. Glenny, Thomas R. Martin, and William A. Altemeier

Computational Identification of Key Biological Modules and Transcription Factors in Acute Lung Injury

Am. J. Respir. Crit. Care Med. 2006; 173: 653-658. First published online December 30 2005 as doi:10.1164/rccm.200509-1473OC [Abstract] [Full Text] [PDF] [Online Supplement]  

D. Cystic Fibrosis:

Richard A. Belkin, Noreen R. Henig, Lianne G. Singer, Cecilia Chaparro, Ronald C. Rubenstein, Sharon X. Xie, Justin Y. Yee, Robert M. Kotloff, David A. Lipson, and Greta R. Bunin

Risk Factors for Death of Patients with Cystic Fibrosis Awaiting Lung Transplantation

Am. J. Respir. Crit. Care Med. 2006; 173: 659-666. First published online December 30 2005 as doi:10.1164/rccm.200410-1369OC [Abstract] [Full Text] [PDF] [Online Supplement]  

E. Environmental and Occupational Lung Disease:

Francine Laden, Joel Schwartz, Frank E. Speizer, and Douglas W. Dockery

Reduction in Fine Particulate Air Pollution and Mortality: Extended Follow-up of the Harvard Six Cities Study

Am. J. Respir. Crit. Care Med. 2006; 173: 667-672. First published online January 19 2006 as doi:10.1164/rccm.200503-443OC [Abstract] [Full Text] [PDF] [Online Supplement]  

F. Pulmonary Infections:

Ian C. Davis, Eduardo R. Lazarowski, Judy M. Hickman-Davis, James A. Fortenberry, Fu-Ping Chen, Xiaodong Zhao, Eric Sorscher, Lee M. Graves, Wayne M. Sullender, and Sadis Matalon

Leflunomide Prevents Alveolar Fluid Clearance Inhibition by Respiratory Syncytial Virus

Am. J. Respir. Crit. Care Med. 2006; 173: 673-682. First published online December 30 2005 as doi:10.1164/rccm.200508-1200OC [Abstract] [Full Text] [PDF]  

CORRESPONDENCE:

Mudit Mathur and Darren Bullock

Oxygenation Index as a Predictor of Outcome in Children with Acute Hypoxemic Respiratory Failure

Am. J. Respir. Crit. Care Med. 2006; 173: 683 [Full Text] [PDF]  

Desmond Bohn, Daniel Trachsel, Brian McCrindle, and Satoshi Nakagawa

Oxygenation Index as a Predictor of Outcome in Children with Acute Hypoxemic Respiratory Failure

Am. J. Respir. Crit. Care Med. 2006; 173: 683a [Full Text] [PDF]  

Thomas Moulding

Failure to Mention Fixed-Dose Drug Combinations in the ATS/CDC/IDSA Tuberculosis Control Statement

Am. J. Respir. Crit. Care Med. 2006; 173: 684 [Full Text] [PDF]  

Charles M. Nolan, Zachery Taylor, and Henry M. Blumberg

Failure to Mention Fixed-Dose Drug Combinations in the ATS/CDC/IDSA Tuberculosis Control Statement

Am. J. Respir. Crit. Care Med. 2006; 173: 684a-685 [Full Text] [PDF]  

Po-Shun Lee and Aaron Waxman

The Importance of Differentiating Gelsolin Isoforms

Am. J. Respir. Crit. Care Med. 2006; 173: 685 [Full Text] [PDF]  

Olga Zegarra-Moran and Luis J. V. Galietta

The Importance of Differentiating Gelsolin Isoforms

Am. J. Respir. Crit. Care Med. 2006; 173: 685a [Full Text] [PDF]  

François Jardin

Tidal Volume Reduction in Patients with Acute Lung Injury When Plateau Pressures Are Not High

Am. J. Respir. Crit. Care Med. 2006; 173: 685b-686 [Full Text] [PDF]  

Kelvin K. Shiu and Mark J. Rosen

Is There a Safe Plateau Pressure Threshold for Patients with Acute Lung Injury and Acute Respiratory Distress Syndrome?

Am. J. Respir. Crit. Care Med. 2006; 173: 686 [Full Text] [PDF]  

David N. Hager, Jerry A. Krishnan, Roy G. Brower, Douglas L. Hayden for the ARDS Network Investigators

Is There a Safe Plateau Pressure Threshold for Patients with Acute Lung Injury and Acute Respiratory Distress Syndrome?

Am. J. Respir. Crit. Care Med. 2006; 173: 687 [Full Text] [PDF]  

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