EDITORIALS:

Peter G. Gibson

Cough Is an Airway Itch?

Am. J. Respir. Crit. Care Med. 2004; 169: 1-2 [Full Text]  

Louis-Philippe Boulet

Allergen-derived T Cell Peptides and Late Asthmatic Responses

Am. J. Respir. Crit. Care Med. 2004; 169: 2-3 [Full Text]  

Jeffrey L. Myers and Moises Selman

Respiratory Epithelium in Usual Interstitial Pneumonia/Idiopathic Pulmonary Fibrosis: Spark or Destructive Flame?

Am. J. Respir. Crit. Care Med. 2004; 169: 3-5 [Full Text]  

Ivan M. Robbins

Advancing Therapy for Pulmonary Arterial Hypertension: Can Animal Models Help?

Am. J. Respir. Crit. Care Med. 2004; 169: 5-6 [Full Text]  

Marc Humbert and Gérald Simonneau

Sildenafil for Pulmonary Arterial Hypertension: Still Waiting for Evidence

Am. J. Respir. Crit. Care Med. 2004; 169: 6-7 [Full Text]  

Erik R. Swenson

Therapeutic Hypercapnic Acidosis: Pushing the Envelope

Am. J. Respir. Crit. Care Med. 2004; 169: 8-9 [Full Text]  

CRITICAL CARE PERSPECTIVE:

Henry J. Silverman, John M. Luce, and Jack Schwartz

Protecting Subjects with Decisional Impairment in Research: The Need for a Multifaceted Approach

Am. J. Respir. Crit. Care Med. 2004; 169: 10-14 [Full Text]  

ARTICLES:

A. Cough and Inflammatory Mediators:

Surinder S. Birring, Debbie Parker, Christopher E. Brightling, Peter Bradding, Andrew J. Wardlaw, and Ian D. Pavord

Induced Sputum Inflammatory Mediator Concentrations in Chronic Cough

Am. J. Respir. Crit. Care Med. 2004; 169: 15-19. First published online September 25 2003 as doi:10.1164/rccm.200308-1092OC [Abstract] [Full Text]  

B. Late Asthmatic Reaction:

F. Runa Ali, William L. G. Oldfield, Noritaka Higashi, Mark Larché, and A. Barry Kay

Late Asthmatic Reactions Induced by Inhalation of Allergen-derived T Cell Peptides

Am. J. Respir. Crit. Care Med. 2004; 169: 20-26. First published online September 18 2003 as doi:10.1164/rccm.200305-690OC [Abstract] [Full Text] [Online Supplement]  

C. Laminin and Idiopathic Pulmonary Fibrosis:

Elisa Lappi-Blanco, Riitta Kaarteenaho-Wiik, Sirpa Salo, Raija Sormunen, Marko Määttä, Helena Autio-Harmainen, Ylermi Soini, and Paavo Pääkkö

Laminin-5 ₂ Chain in Cryptogenic Organizing Pneumonia and Idiopathic Pulmonary Fibrosis

Am. J. Respir. Crit. Care Med. 2004; 169: 27-33. First published online September 18 2003 as doi:10.1164/rccm.200210-1234OC [Abstract] [Full Text]  

D. Sildenafil Beraprost and Pulmonary Hypertension:

Takefumi Itoh, Noritoshi Nagaya, Takafumi Fujii, Takashi Iwase, Norifumi Nakanishi, Kaoru Hamada, Kenji Kangawa, and Hiroshi Kimura

A Combination of Oral Sildenafil and Beraprost Ameliorates Pulmonary Hypertension in Rats

Am. J. Respir. Crit. Care Med. 2004; 169: 34-38. First published online October 2 2003 as doi:10.1164/rccm.200303-346OC [Abstract] [Full Text]  

E. Sildenafil and Pulmonary Hypertension:

Ralph T. Schermuly, Klaus P. Kreisselmeier, Hossein A. Ghofrani, Hüseyin Yilmaz, Ghazwan Butrous, Leander Ermert, Monika Ermert, Norbert Weissmann, Frank Rose, Andreas Guenther, Dieter Walmrath, Werner Seeger, and Friedrich Grimminger

Chronic Sildenafil Treatment Inhibits Monocrotaline-induced Pulmonary Hypertension in Rats

Am. J. Respir. Crit. Care Med. 2004; 169: 39-45. First published online September 4 2003 as doi:10.1164/rccm.200302-282OC [Abstract] [Full Text]  

F. Hypercapnia and Lung Injury:

John G. Laffey, Dave Honan, Natalie Hopkins, Jean-Marc Hyvelin, John F. Boylan, and Paul McLoughlin

Hypercapnic Acidosis Attenuates Endotoxin-induced Acute Lung Injury

Am. J. Respir. Crit. Care Med. 2004; 169: 46-56. First published online September 4 2003 as doi:10.1164/rccm.200205-394OC [Abstract] [Full Text] [Online Supplement]  

G. Alveolar Instability and Ventilator Injury:

Jay M. Steinberg, Henry J. Schiller, Jeffrey M. Halter, Louis A. Gatto, Hsi-Ming Lee, Lucio A. Pavone, and Gary F. Nieman

Alveolar Instability Causes Early Ventilator-induced Lung Injury Independent of Neutrophils

Am. J. Respir. Crit. Care Med. 2004; 169: 57-63. First published online October 2 2003 as doi:10.1164/rccm.200304-544OC [Abstract] [Full Text] [Online Supplement]  

H. Exhaled Condensate after Surgery:

Edward D. Moloney, Sharon E. Mumby, Reka Gajdocsi, Julius H. Cranshaw, Sergei A. Kharitonov, Gregory J. Quinlan, and Mark J. Griffiths

Exhaled Breath Condensate Detects Markers of Pulmonary Inflammation after Cardiothoracic Surgery

Am. J. Respir. Crit. Care Med. 2004; 169: 64-69. First published online October 9 2003 as doi:10.1164/rccm.200307-1005OC [Abstract] [Full Text] [Online Supplement]  

I. Wheezing Infancy and Interferon:

Stefano Guerra, I. Carla Lohman, Marilyn Halonen, Fernando D. Martinez, and Anne L. Wright

Reduced Interferon Production and Soluble CD14 Levels in Early Life Predict Recurrent Wheezing by 1 Year of Age

Am. J. Respir. Crit. Care Med. 2004; 169: 70-76. First published online October 2 2003 as doi:10.1164/rccm.200304-499OC [Abstract] [Full Text]  

J. Cystic Fibrosis and Bone:

Robert M. Aris, Gayle E. Lester, Melissa Caminiti, A. Denene Blackwood, Margaret Hensler, Robert K. Lark, Travis M. Hecker, Jordan B. Renner, Ursula Guillen, Sue A. Brown, Isabel P. Neuringer, Worakij Chalermskulrat, and David A. Ontjes

Efficacy of Alendronate in Adults with Cystic Fibrosis with Low Bone Density

Am. J. Respir. Crit. Care Med. 2004; 169: 77-82. First published online October 16 2003 as doi:10.1164/rccm.200307-1049OC [Abstract] [Full Text]  

K. Corticosteroids and Fractures:

Samy Suissa, Marc Baltzan, Richard Kremer, and Pierre Ernst

Inhaled and Nasal Corticosteroid Use and the Risk of Fracture

Am. J. Respir. Crit. Care Med. 2004; 169: 83-88. First published online October 9 2003 as doi:10.1164/rccm.200305-640OC [Abstract] [Full Text] [Online Supplement]  

L. Exercise Muscles Oxygen and COPD:

Russell S. Richardson, Bryan T. Leek, Timothy P. Gavin, Luke J. Haseler, Sundar R. D. Mudaliar, Robert Henry, Odile Mathieu-Costello, and Peter D. Wagner

Reduced Mechanical Efficiency in Chronic Obstructive Pulmonary Disease but Normal Peak O₂ with Small Muscle Mass Exercise

Am. J. Respir. Crit. Care Med. 2004; 169: 89-96. First published online September 18 2003 as doi:10.1164/rccm.200305-627OC [Abstract] [Full Text] [Online Supplement]  

M. Airway Biology and Integrin:

William M. Abraham, Ashfaq Ahmed, Irakli Serebriakov, Amie N. Carmillo, Janine Ferrant, Antonin R. de Fougerolles, Ellen A. Garber, Philip J. Gotwals, Victor E. Koteliansky, Fred Taylor, and Roy R. Lobb

A Monoclonal Antibody to 1ß1 Blocks Antigen-induced Airway Responses in Sheep

Am. J. Respir. Crit. Care Med. 2004; 169: 97-104. First published online October 24 2003 as doi:10.1164/rccm.200304-543OC [Abstract] [Full Text]  

N. Murine Allergic Rhinitis:

Tohru Watanabe, Mitsuhiro Okano, Hisashi Hattori, Tadashi Yoshino, Nobuaki Ohno, Nobuo Ohta, Yuji Sugata, Yorihisa Orita, Toshiyuki Takai, and Kazunori Nishizaki

Roles of FcRIIB in Nasal Eosinophilia and IgE Production in Murine Allergic Rhinitis

Am. J. Respir. Crit. Care Med. 2004; 169: 105-112. First published online October 2 2003 as doi:10.1164/rccm.200302-239OC [Abstract] [Full Text]  

O. Paclitaxel Hypersensitivity and Sensory Peptides:

Yoshinori Itoh, Toshiaki Sendo, Toshio Hirakawa, Takeshi Goromaru, Shinya Takasaki, Hideaki Yahata, Hitoo Nakano, and Ryozo Oishi

Role of Sensory Nerve Peptides Rather than Mast Cell Histamine in Paclitaxel Hypersensitivity

Am. J. Respir. Crit. Care Med. 2004; 169: 113-119. First published online October 16 2003 as doi:10.1164/rccm.200307-901OC [Abstract] [Full Text]  

P. Number of Alveoli:

Matthias Ochs, Jens R. Nyengaard, Anja Jung, Lars Knudsen, Marion Voigt, Thorsten Wahlers, Joachim Richter, and Hans Jørgen G. Gundersen

The Number of Alveoli in the Human Lung

Am. J. Respir. Crit. Care Med. 2004; 169: 120-124. First published online September 25 2003 as doi:10.1164/rccm.200308-1107OC [Abstract] [Full Text] [Online Supplement]  

Q. Indolent SARS:

Man-Fai Lam, Gaik C. Ooi, Bing Lam, James C. Ho, Wing H. Seto, Pak L. Ho, Poon C. Wong, Raymond Liang, Wah K. Lam, and Kenneth W. Tsang

An Indolent Case of Severe Acute Respiratory Syndrome

Am. J. Respir. Crit. Care Med. 2004; 169: 125-128 [Abstract] [Full Text]  

CORRESPONDENCE:

Randolph J. Lipchik, Lawrence R. Goodman, Arnaud Perrier, Mathieu Nendaz, François Sarasin, Henri Bounameaux, and Nigel Howarth

Cost-effectiveness of Computed Tomography in Diagnosis of Pulmonary Embolism

Am. J. Respir. Crit. Care Med. 2004; 169: 129-130 [Full Text]  

Mihai S. Jalba, Gustavo J. Rodrigo, Carlos Rodrigo, Carlos A. Camargo, Jr., Marie-Pierre Malice, Stuart A. Green, and Theodore F. Reiss

Intravenous Montelukast in Acute Asthma

Am. J. Respir. Crit. Care Med. 2004; 169: 130-131 [Full Text]  

Christopher E. Brightling, Ian D. Pavord, Patrick T. Flood-Page, Andrew N. Menzies-Gow, A. Barry Kay, and Douglas S. Robinson

Eosinophils in Asthma and Airway Hyperresponsiveness

Am. J. Respir. Crit. Care Med. 2004; 169: 131-133 [Full Text]  

Esteban C. Gabazza, Osamu Taguchi, and Yukihiko Adachi

Do Matrix Metalloproteinases Protect or Worsen Pneumonia?

Am. J. Respir. Crit. Care Med. 2004; 169: 133 [Full Text]  

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