EDITORIALS:

Jeffrey A. Whitsett

Genetic Basis of Familial Interstitial Lung Disease: Misfolding or Function of Surfactant Protein C?

Am. J. Respir. Crit. Care Med. 2002; 165: 1201-1202. [Full Text]  

Richard W. Light

Manual Aspiration: The Preferred Method for Managing Primary Spontaneous Pneumothorax?

Am. J. Respir. Crit. Care Med. 2002; 165: 1202-1203. [Full Text]  

T. Douglas Bradley

Crossing the Threshold: Implications for Central Sleep Apnea

Am. J. Respir. Crit. Care Med. 2002; 165: 1203-1204. [Full Text]  

PRO/CON EDITORIALS:

Jack Gauldie

Inflammatory Mechanisms Are a Minor Component of the Pathogenesis of Idiopathic Pulmonary Fibrosis

Am. J. Respir. Crit. Care Med. 2002; 165: 1205-1206. [Full Text]  

Robert M. Strieter

Inflammatory Mechanisms Are Not a Minor Component of the Pathogenesis of Idiopathic Pulmonary Fibrosis

Am. J. Respir. Crit. Care Med. 2002; 165: 1206-1207. [Full Text]  

Jack Gauldie

Rebuttal from Dr. Gauldie

Am. J. Respir. Crit. Care Med. 2002; 165: 1207-1208. [Full Text]  

Robert M. Strieter

Rebuttal from Dr. Strieter

Am. J. Respir. Crit. Care Med. 2002; 165: 1208. [Full Text]  

PULMONARY PERSPECTIVE:

Marius M. Hoeper, Nazzareno Galiè, Gerald Simonneau, and Lewis J. Rubin

New Treatments for Pulmonary Arterial Hypertension

Am. J. Respir. Crit. Care Med. 2002; 165: 1209-1216. [Full Text]  

STATE OF THE ART:

Terry Young, Paul E. Peppard, and Daniel J. Gottlieb

Epidemiology of Obstructive Sleep Apnea: A Population Health Perspective

Am. J. Respir. Crit. Care Med. 2002; 165: 1217-1239. [Abstract] [Full Text]  

ARTICLES:

A. Interstitial Lung Disease:

Alan Q. Thomas, Kirk Lane, John Phillips, III, Melissa Prince, Cheryl Markin, Marcy Speer, David A. Schwartz, Radhika Gaddipati, Annis Marney, Joyce Johnson, Richard Roberts, Jonathan Haines, Mildred Stahlman, and James E. Loyd

Heterozygosity for a Surfactant Protein C Gene Mutation Associated with Usual Interstitial Pneumonitis and Cellular Nonspecific Interstitial Pneumonitis in One Kindred

Am. J. Respir. Crit. Care Med. 2002; 165: 1322-1328. [Abstract] [Full Text]  

B. Pneumothorax:

Marc Noppen, Patrick Alexander, Peter Driesen, Hans Slabbynck, and André Verstraeten

Manual Aspiration versus Chest Tube Drainage in First Episodes of Primary Spontaneous Pneumothorax: A Multicenter, Prospective, Randomized Pilot Study

Am. J. Respir. Crit. Care Med. 2002; 165: 1240-1244. [Abstract] [Full Text]  

C. Sleep-disordered Breathing:

Ailiang Xie, James B. Skatrud, Dominic S. Puleo, Peter S. Rahko, and Jerome A. Dempsey

Apnea–Hypopnea Threshold for CO₂ in Patients with Congestive Heart Failure

Am. J. Respir. Crit. Care Med. 2002; 165: 1245-1250. [Abstract] [Full Text]  

Hideaki Nakayama, Curtis A. Smith, Joshua R. Rodman, James B. Skatrud, and Jerome A. Dempsey

Effect of Ventilatory Drive on Carbon Dioxide Sensitivity below Eupnea during Sleep

Am. J. Respir. Crit. Care Med. 2002; 165: 1251-1260. [Abstract] [Full Text]  

D. Control of Breathing:

Thomas Brack, Amal Jubran, and Martin J. Tobin

Dyspnea and Decreased Variability of Breathing in Patients with Restrictive Lung Disease

Am. J. Respir. Crit. Care Med. 2002; 165: 1260-1264. [Abstract] [Full Text] [Online Data Supplement]  

E. Respiratory Muscles:

Nicholas Hart, Annabel H. Nickol, Derek Cramer, Simon P. Ward, Frédéric Lofaso, Neil B. Pride, John Moxham, and Michael I. Polkey

Effect of Severe Isolated Unilateral and Bilateral Diaphragm Weakness on Exercise Performance

Am. J. Respir. Crit. Care Med. 2002; 165: 1265-1270. [Abstract] [Full Text] [Online Data Supplement]  

F. Mechanical Ventilation:

Gabriella de Durante, Monica del Turco, Laura Rustichini, Patrizia Cosimini, Francesco Giunta, Leonard D. Hudson, Arthur S. Slutsky, and V. Marco Ranieri

ARDSNet Lower Tidal Volume Ventilatory Strategy May Generate Intrinsic Positive End-Expiratory Pressure in Patients with Acute Respiratory Distress Syndrome

Am. J. Respir. Crit. Care Med. 2002; 165: 1271-1274. [Abstract] [Full Text]  

G. Asthma and Airway Biology:

Elizabeth L. J. Van Rensen, Pieter S. Hiemstra, Klaus F. Rabe, and Peter J. Sterk

Assessment of Microvascular Leakage via Sputum Induction: The Role of Substance P and Neurokinin A in Patients with Asthma

Am. J. Respir. Crit. Care Med. 2002; 165: 1275-1279. [Abstract] [Full Text]  

Els Palmans, Nele J. Vanacker, Romain A. Pauwels, and Johan C. Kips

Effect of Age on Allergen-induced Structural Airway Changes in Brown Norway Rats

Am. J. Respir. Crit. Care Med. 2002; 165: 1280-1284. [Abstract] [Full Text]  

John P. Kress, Imre Noth, Brian K. Gehlbach, Nitin Barman, Anne S. Pohlman, Annette Miller, Sherwin Morgan, and Jesse B. Hall

The Utility of Albuterol Nebulized with Heliox during Acute Asthma Exacerbations

Am. J. Respir. Crit. Care Med. 2002; 165: 1317-1321. [Abstract] [Full Text]  

H. Diesel Exhaust Particles:

Hirohisa Takano, Rie Yanagisawa, Takamichi Ichinose, Kaori Sadakane, Shin Yoshino, Toshikazu Yoshikawa, and Masatoshi Morita

Diesel Exhaust Particles Enhance Lung Injury Related to Bacterial Endotoxin through Expression of Proinflammatory Cytokines, Chemokines, and Intercellular Adhesion Molecule-1

Am. J. Respir. Crit. Care Med. 2002; 165: 1329-1335. [Abstract] [Full Text] [Online Data Supplement]  

I. Pediatric Lung Disease:

Nikolaos G. Papadopoulos, Maria Moustaki, Mariza Tsolia, Apostolos Bossios, Eleni Astra, Anargiroula Prezerakou, Dimitrios Gourgiotis, and Dimitrios Kafetzis

Association of Rhinovirus Infection with Increased Disease Severity in Acute Bronchiolitis

Am. J. Respir. Crit. Care Med. 2002; 165: 1285-1289. [Abstract] [Full Text]  

Sukhbir K. Shahid, Sergei A. Kharitonov, Nicola M. Wilson, Andrew Bush, and Peter J. Barnes

Increased Interleukin-4 and Decreased Interferon- in Exhaled Breath Condensate of Children with Asthma

Am. J. Respir. Crit. Care Med. 2002; 165: 1290-1293. [Abstract] [Full Text]  

Stephen W. Turner, Lyle J. Palmer, Peter J. Rye, Neil A. Gibson, Parveenjeet K. Judge, Sally Young, Louis I. Landau, and Peter N. Le Souëf

Infants with Flow Limitation at 4 Weeks: Outcome at 6 and 11 Years

Am. J. Respir. Crit. Care Med. 2002; 165: 1294-1298. [Abstract] [Full Text] [Online Data Supplement]  

J. Lung Function:

Tricia M. McKeever, Sarah Scrivener, Emma Broadfield, Zoe Jones, John Britton, and Sarah A. Lewis

Prospective Study of Diet and Decline in Lung Function in a General Population

Am. J. Respir. Crit. Care Med. 2002; 165: 1299-1303. [Abstract] [Full Text]  

Claudio Tantucci, Alexandre Duguet, Pietro Giampiccolo, Thomas Similowski, Marc Zelter, and Jean-Philippe Derenne

The Best Peak Expiratory Flow Is Flow-Limited and Effort-Independent in Normal Subjects

Am. J. Respir. Crit. Care Med. 2002; 165: 1304-1308. [Abstract] [Full Text]  

K. Sickle Cell Anemia:

Leigh A. Callahan, Kristy F. Woods, George A. Mensah, Leigh T. Ramsey, Paule Barbeau, and Bernard Gutin

Cardiopulmonary Responses to Exercise in Women with Sickle Cell Anemia

Am. J. Respir. Crit. Care Med. 2002; 165: 1309-1316. [Abstract] [Full Text]  

CORRESPONDENCE:

Riccardo Polosa, Maarten van den Berge, Huib A. M. Kerstjens, and Dirkie S. Postma

ADENOSINE MONOPHOSPHATE CHALLENGE AND MONITORING OF AIRWAY RESPONSE TO ANTIINFLAMMATORY THERAPY

Am. J. Respir. Crit. Care Med. 2002; 165: 1336. [Full Text]  

Peter D. Wagner, Michael B. Reid, Roberto A. Rabinovich, and Josep Roca

IS COPD ALSO A DISEASE OF SKELETAL MUSCLE?

Am. J. Respir. Crit. Care Med. 2002; 165: 1336-a-1338. [Full Text]  

A. Ross Hill, David L. Cohn, and Richard J. O'Brien

"TREATMENT OF LTBI": SELLING POINT OR SEMANTIC BLUNDER?

Am. J. Respir. Crit. Care Med. 2002; 165: 1338. [Full Text]  

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