ELECTRONIC PAGES:

[CORRESPONDENCE. Edward R. Carter. An Encounter with Dr. Otis]

EDITORIALS:

Zachary Taylor and Richard J. O'Brien

Tuberculosis Elimination . Are We Willing to Pay the Price?

Am. J. Respir. Crit. Care Med. 2001; 163: 1-2. [Full text]  

Didier Dreyfuss and Georges Saumon

Pressure-Volume Curves . Searching for the Grail or Laying Patients with Adult Respiratory Distress Syndrome on Procrustes' Bed?

Am. J. Respir. Crit. Care Med. 2001; 163: 2-3. [Full text]  

Richard Beasley and Julian Crane

Reducing Asthma Mortality with the Asthma Self-Management Plan System of Care

Am. J. Respir. Crit. Care Med. 2001; 163: 3-4. [Full text]  

Jan Hedner and Ludger Grote

The Link between Sleep Apnea and Cardiovascular Disease . Time to Target the Nonsleepy Sleep Apneics?

Am. J. Respir. Crit. Care Med. 2001; 163: 5-6. [Full text]  

HOW IT REALLY HAPPENED:

RICHARD L. RILEY

What Nobody Needs to Know About Airborne Infection

Am. J. Respir. Crit. Care Med. 2001; 163: 7-8. [Full text]  

OCCASIONAL ESSAYS:

RICHARD K. ALBERT

The Buck Stops Here

Am. J. Respir. Crit. Care Med. 2001; 163: 9-10. [Full text]  

RICHARD A. COOPER

The COMPACCS Study . Questions Left Unanswered

Am. J. Respir. Crit. Care Med. 2001; 163: 10-11. [Full text]  

ARTICLES:

Asthma, Airway Biology and COPD:

MICHAEL J. ABRAMSON, MICHAEL J. BAILEY, FIONA J. COUPER, JAN S. DRIVER, OLAF H. DRUMMER, ANDREW B. FORBES, JOHN J. MCNEIL, E. HAYDN WALTERS, and the Victorian Asthma Mortality Study Group

Are Asthma Medications and Management Related to Deaths from Asthma?

Am. J. Respir. Crit. Care Med. 2001; 163: 12-18. [Abstract] [Full text]  

PETER G. GIBSON, NICHOLAS SALTOS, and KELLIE FAKES

Acute Anti-inflammatory Effects of Inhaled Budesonide in Asthma . A Randomized Controlled Trial

Am. J. Respir. Crit. Care Med. 2001; 163: 32-36. [Abstract] [Full text]  

KENT A. GRIFFITH, DUANE L. SHERRILL, ERIN M. SIEGEL, TERI A. MANOLIO, HORACE W. BONEKAT, and PAUL L. ENRIGHT

Predictors of Loss of Lung Function in the Elderly . The Cardiovascular Health Study

Am. J. Respir. Crit. Care Med. 2001; 163: 61-68. [Abstract] [Full text]  

DEBORAH COOK, GORDON GUYATT, ERIC WONG, ROGER GOLDSTEIN, MICHEL BEDARD, PEGGY AUSTIN, HELEN RAMSDALE, ROMAN JAESCHKE, and MALCOLM SEARS

Regular Versus As-Needed Short-Acting Inhaled -Agonist Therapy for Chronic Obstructive Pulmonary Disease

Am. J. Respir. Crit. Care Med. 2001; 163: 85-90. [Abstract] [Full text]  

DAVID RAMOS-BARBÓN, MASARU SUZUKI, RAME TAHA, SOPHIE MOLET, THOMAS B. ISSEKUTZ, QUTAYBA HAMID, and JAMES G. MARTIN

Effect of ₄-Integrin Blockade on CD4⁺ Cell-driven Late Airway Responses in the Rat

Am. J. Respir. Crit. Care Med. 2001; 163: 101-108. [Abstract] [Full text]  

SALLY SPENCER, PETER M. A. CALVERLEY, P. SHERWOOD BURGE, and PAUL W. JONES

Health Status Deterioration in Patients with Chronic Obstructive Pulmonary Disease

Am. J. Respir. Crit. Care Med. 2001; 163: 122-128. [Abstract] [Full text]  

MERITXELL PASTO, ELIE SERRANO, EMANUELLE UROCOSTE, MARIE-ALINE BARBACANNE, ANNIE GUISSANI, ALAIN DIDIER, MARIE-BERNADETTE DELISLE, JACQUES RAMI, and JEAN-FRANÇOIS ARNAL

Nasal Polyp-Derived Superoxide Anion . Dose-Dependent Inhibition by Nitric Oxide and Pathophysiological Implications

Am. J. Respir. Crit. Care Med. 2001; 163: 145-151. [Abstract] [Full text]  

ARIHIKO KANEHIRO, TOSHIHIDE IKEMURA, MIKA J. MÄKELÄ, MICHAEL LAHN, ANTHONY JOETHAM, AZZEDDINE DAKHAMA, and ERWIN W. GELFAND

Inhibition of Phosphodiesterase 4 Attenuates Airway Hyperresponsiveness and Airway Inflammation in a Model of Secondary Allergen Challenge

Am. J. Respir. Crit. Care Med. 2001; 163: 173-184. [Abstract] [Full text]  

CHARLES PILETTE, VÉRONIQUE GODDING, ROBERT KISS, MONIQUE DELOS, ERIC VERBEKEN, CHRISTINE DECAESTECKER, KRISTEL DE PAEPE, JEAN-PIERRE VAERMAN, MARC DECRAMER, and YVES SIBILLE

Reduced Epithelial Expression of Secretory Component in Small Airways Correlates with Airflow Obstruction in Chronic Obstructive Pulmonary Disease

Am. J. Respir. Crit. Care Med. 2001; 163: 185-194. [Abstract] [Full text]  

HIROSHI MUKAE, RENAUD VINCENT, KEVIN QUINLAN, DEAN ENGLISH, JENNIFER HARDS, JAMES C. HOGG, and STEPHAN F. van EEDEN

The Effect of Repeated Exposure to Particulate Air Pollution (PM₁₀) on the Bone Marrow

Am. J. Respir. Crit. Care Med. 2001; 163: 201-209. [Abstract] [Full text]  

DAVID J. FIGUEROA, RICHARD M. BREYER, STEPHANIE K. DEFOE, STACIA KARGMAN, BRUCE L. DAUGHERTY, KRISTINE WALDBURGER, QINGYUN LIU, MICHELLE CLEMENTS, ZHIZEN ZENG, GARY P. O'NEILL, THOMAS R. JONES, KEVIN R. LYNCH, CHRISTOPHER P. AUSTIN, and JILLY F. EVANS

Expression of the Cysteinyl Leukotriene 1 Receptor in Normal Human Lung and Peripheral Blood Leukocytes

Am. J. Respir. Crit. Care Med. 2001; 163: 226-233. [Abstract] [Full text]  

MARIA ROSA ACCOMAZZO, GIAN ENRICO ROVATI, TERESA VIGANÒ, ALICIA HERNANDEZ, ALBINO BONAZZI, MANLIO BOLLA, FRANCESCA FUMAGALLI, SERENA VIAPPIANI, ELISABETTA GALBIATI, SAULA RAVASI, CHIARA ALBERTONI, MONICA DI LUCA, ANTONIO CAPUTI, PIERO ZANNINI, GIUSEPPE CHIESA, ANNA MARIA VILLA, SILVIA MARIA DOGLIA, GIANCARLO FOLCO, and SIMONETTA NICOSIA

Leukotriene D₄-Induced Activation of Smooth-Muscle Cells From Human Bronchi Is Partly Ca²⁺-Independent

Am. J. Respir. Crit. Care Med. 2001; 163: 266-272. [Abstract] [Full text]  

OLLI M. PITKÄNEN, DAVID SMITH, HUGH O'BRODOVICH, and GAIL OTULAKOWSKI

Expression of -, -, and -hENaC mRNA in the Human Nasal, Bronchial, and Distal Lung Epithelium

Am. J. Respir. Crit. Care Med. 2001; 163: 273-276. [Abstract] [Full text]  

GABRIELE BOLTE, CHRISTIAN FRYE, BERND HOELSCHER, INES MEYER, MATTHIAS WJST, and JOACHIM HEINRICH

Margarine Consumption and Allergy in Children

Am. J. Respir. Crit. Care Med. 2001; 163: 277-279. [Abstract] [Full text]  

Neonatal Lung Disease:

LYLE J. PALMER, PETER J. RYE, NEIL A. GIBSON, PAUL R. BURTON, LOUIS I. LANDAU, and PETER N. LESOUËF

Airway Responsiveness in Early Infancy Predicts Asthma, Lung Function, and Respiratory Symptoms by School Age

Am. J. Respir. Crit. Care Med. 2001; 163: 37-42. [Abstract] [Full text]  

PAOLA CAVICCHIOLI, LUC J. I. ZIMMERMANN, PAOLA E. COGO, TAMARA BADON, GIUSEPPE GIORDANO, MIRKA TORRESIN, FRANCO ZACCHELLO, and VIRGILIO P. CARNIELLI

Endogenous Surfactant Turnover in Preterm Infants with Respiratory Distress Syndrome Studied with Stable Isotope Lipids

Am. J. Respir. Crit. Care Med. 2001; 163: 55-60. [Abstract] [Full text]  

ROBERT S. TEPPER, TAMICA WILLIAMS, JEFF KISLING, and ROBERT CASTILE

Static Compliance of the Respiratory System in Healthy Infants

Am. J. Respir. Crit. Care Med. 2001; 163: 91-94. [Abstract] [Full text]  

JOHN ELLIOT, NEIL CARROLL, MARY BOSCO, MARY MCCROHAN, and PHIL ROBINSON

Increased Airway Responsiveness and Decreased Alveolar Attachment Points Following In Utero Smoke Exposure in the Guinea Pig

Am. J. Respir. Crit. Care Med. 2001; 163: 140-144. [Abstract] [Full text]  

BORIS W. KRAMER, ALAN H. JOBE, CINDY J. BACHURSKI, and MACHIKO IKEGAMI

Surfactant Protein A Recruits Neutrophils into the Lungs of Ventilated Preterm Lambs

Am. J. Respir. Crit. Care Med. 2001; 163: 158-165. [Abstract] [Full text]  

Sepsis, Acute Lung Injury, Mechanical Ventilation, and Ethics:

MASAHIKO TSUCHIYA, AKIRA ASADA, KEIKO MAEDA, YASUYO UEDA, EISUKE F. SATO, MITSUO SHINDO, and MASAYASU INOUE

Propofol versus Midazolam Regarding Their Antioxidant Activities

Am. J. Respir. Crit. Care Med. 2001; 163: 26-31. [Abstract] [Full text]  

KEITH G. HICKLING

Best Compliance during a Decremental, But Not Incremental, Positive End-Expiratory Pressure Trial Is Related to Open-Lung Positive End-Expiratory Pressure . A Mathematical Model of Acute Respiratory Distress Syndrome Lungs

Am. J. Respir. Crit. Care Med. 2001; 163: 69-78. [Abstract] [Full text]  

TADATSURA KOSHIKA, AKITOSHI ISHIZAKA, ITSUO NAGATOMI, YUJI SUDO, NAOKI HASEGAWA, and TOSHIO GOTO

Pretreatment with FK506 Improves Survival Rate and Gas Exchange in Canine Model of Acute Lung Injury

Am. J. Respir. Crit. Care Med. 2001; 163: 79-84. [Abstract] [Full text]  

REINHOLD SCHMIDT, UTE MEIER, MARIFE YABUT-PEREZ, DIETER WALMRATH, FRIEDRICH GRIMMINGER, WERNER SEEGER, and ANDREAS GÜNTHER

Alteration of Fatty Acid Profiles in Different Pulmonary Surfactant Phospholipids in Acute Respiratory Distress Syndrome and Severe Pneumonia

Am. J. Respir. Crit. Care Med. 2001; 163: 95-100. [Abstract] [Full text]  

MARK L. GOODE, JAMES B. FINK, RAJIV DHAND, and MARTIN J. TOBIN

Improvement in Aerosol Delivery with Helium-Oxygen Mixtures during Mechanical Ventilation

Am. J. Respir. Crit. Care Med. 2001; 163: 109-114. [Abstract] [Full text]  

ELIE AZOULAY, FRÉDÉRIC POCHARD, SYLVIE CHEVRET, FRANÇOIS LEMAIRE, MUSTAFA MOKHTARI, JEAN-ROGER LE GALL, JEAN FRANÇOIS DHAINAUT, and BENOÎT SCHLEMMER

Meeting the Needs of Intensive Care Unit Patient Families . A Multicenter Study

Am. J. Respir. Crit. Care Med. 2001; 163: 135-139. [Abstract] [Full text]  

SHA ZHU, LORRAINE B. WARE, THOMAS GEISER, MICHAEL A. MATTHAY, and SADIS MATALON

Increased Levels of Nitrate and Surfactant Protein A Nitration in the Pulmonary Edema Fluid of Patients with Acute Lung Injury

Am. J. Respir. Crit. Care Med. 2001; 163: 166-172. [Abstract] [Full text]  

MBITHE MUTUNGA, BARBARA FULTON, ROBERT BULLOCK, ANNA BATCHELOR, ALISTER GASCOIGNE, JIM I. GILLESPIE, and SIMON V. BAUDOUIN

Circulating Endothelial Cells in Patients with Septic Shock

Am. J. Respir. Crit. Care Med. 2001; 163: 195-200. [Abstract] [Full text]  

RÉMI NEVIÈRE, HAROLD FAUVEL, CLAUDE CHOPIN, PIERRE FORMSTECHER, and PHILIPPE MARCHETTI

Caspase Inhibition Prevents Cardiac Dysfunction and Heart Apoptosis in a Rat Model of Sepsis

Am. J. Respir. Crit. Care Med. 2001; 163: 218-225. [Abstract] [Full text]  

GUSTAVO MATUTE-BELLO, CHARLES W. FREVERT, OSAMU KAJIKAWA, SHAWN J. SKERRETT, RICHARD B. GOODMAN, DAVID R. PARK, and THOMAS R. MARTIN

Septic Shock and Acute Lung Injury in Rabbits with Peritonitis . Failure of the Neutrophil Response to Localized Infection

Am. J. Respir. Crit. Care Med. 2001; 163: 234-243. [Abstract] [Full text]  

Sleep and Neuromuscular Control of Breathing:

EYAL SHAHAR, CORALYN W. WHITNEY, SUSAN REDLINE, ELISA T. LEE, ANNE B. NEWMAN, F. JAVIER NIETO, GEORGE T. O'CONNOR, LORI L. BOLAND, JOSEPH E. SCHWARTZ, and JONATHAN M. SAMET

Sleep-disordered Breathing and Cardiovascular Disease . Cross-sectional Results of the Sleep Heart Health Study

Am. J. Respir. Crit. Care Med. 2001; 163: 19-25. [Abstract] [Full text]  

DIMITRI LEDUC, ERIC BRUNKO, and ANDRÉ DE TROYER

Response of the Canine Internal Intercostal Muscles to Chest Wall Vibration

Am. J. Respir. Crit. Care Med. 2001; 163: 49-54. [Abstract] [Full text]  

MAREE A. MILROSS, AMANDA J. PIPER, MARK NORMAN, HEINRICH F. BECKER, GRANT N. WILLSON, RONALD R. GRUNSTEIN, COLIN E. SULLIVAN, and PETER T. P. BYE

Low-flow Oxygen and Bilevel Ventilatory Support . Effects on Ventilation during Sleep in Cystic Fibrosis

Am. J. Respir. Crit. Care Med. 2001; 163: 129-134. [Abstract] [Full text] [Online Data Supplement]  

Transplantation and Pulmonary Fibrosis:

CECILIA CHAPARRO, JANET MAURER, CARLOS GUTIERREZ, MEL KRAJDEN, CHARLIE CHAN, TIMOTHY WINTON, SHAFF KESHAVJEE, MASSINA SCAVUZZO, ELIZABETH TULLIS, MICHAEL HUTCHEON, and STEVEN KESTEN

Infection with Burkholderia cepacia in Cystic Fibrosis . Outcome Following Lung Transplantation

Am. J. Respir. Crit. Care Med. 2001; 163: 43-48. [Abstract] [Full text]  

JAN WAHLSTRÖM, KIANOOSH KATCHAR, HANS WIGZELL, OLLE OLERUP, ANDERS EKLUND, and JOHAN GRUNEWALD

Analysis of Intracellular Cytokines in CD4⁺ and CD8⁺ Lung and Blood T Cells in Sarcoidosis

Am. J. Respir. Crit. Care Med. 2001; 163: 115-121. [Abstract] [Full text]  

SHU HASHIMOTO, YASUHIRO GON, IKUKO TAKESHITA, KEN MATSUMOTO, SHUICHIRO MARUOKA, and TAKASHI HORIE

Transforming Growth Factor-₁ Induces Phenotypic Modulation of Human Lung Fibroblasts to Myofibroblast Through a c-Jun-NH₂-Terminal Kinase-Dependent Pathway

Am. J. Respir. Crit. Care Med. 2001; 163: 152-157. [Abstract] [Full text]  

YASUO SHIMIZU, KUNIO DOBASHI, KUNIHIKO IIZUKA, TAKEO HORIE, KOUKI SUZUKI, HIDEO TUKAGOSHI, TUGIO NAKAZAWA, YOICHI NAKAZATO, and MASATOMO MORI

Contribution of Small GTPase Rho and Its Target Protein ROCK in a Murine Model of Lung Fibrosis

Am. J. Respir. Crit. Care Med. 2001; 163: 210-217. [Abstract] [Full text]  

LUIS A. ORTIZ, JOSEPH LASKY, EVELYNE GOZAL, VICTOR RUIZ, GIUSEPPE LUNGARELLA, ELEONORA CAVARRA, ARNOLD R. BRODY, MITCHELL FRIEDMAN, ANNIE PARDO, and MOISES SELMAN

Tumor Necrosis Factor Receptor Deficiency Alters Matrix Metalloproteinase 13/Tissue Inhibitor of Metalloproteinase 1 Expression in Murine Silicosis

Am. J. Respir. Crit. Care Med. 2001; 163: 244-252. [Abstract] [Full text]  

GALINA D. STRIZHEVA, THOMAS CARSILLO, WARREN D. KRUGER, EUGENE J. SULLIVAN, JAY H. RYU, and ELIZABETH PETRI HENSKE

The Spectrum of Mutations in TSC1 and TSC2 in Women with Tuberous Sclerosis and Lymphangiomyomatosis

Am. J. Respir. Crit. Care Med. 2001; 163: 253-258. [Abstract] [Full text]  

ANDREW J. FISHER, SEAMAS C. DONNELLY, NIKHIL HIRANI, CHRISTOPHER HASLETT, ROBERT M. STRIETER, JOHN H. DARK, and PAUL A. CORRIS

Elevated Levels of Interleukin-8 in Donor Lungs Is Associated with Early Graft Failure after Lung Transplantation

Am. J. Respir. Crit. Care Med. 2001; 163: 259-265. [Abstract] [Full text]  

NHLBI WORKSHOP SUMMARY:

ROGER G. SPRAGG and JAMES F. LEWIS

Pathology of the Surfactant System of the Mature Lung . Second San Diego Conference

Am. J. Respir. Crit. Care Med. 2001; 163: 280-282. [Full text]  

AMERICAN THORACIC SOCIETY:

International Consensus Conferences in Intensive Care Medicine: Noninvasive Positive Pressure Ventilation in Acute Respiratory Failure . Organized Jointly by the American Thoracic Society, the European Respiratory Society, the European Society of Intensive Care Medicine, and the Société de Réanimation de Langue Française, and approved by the ATS Board of Directors, December 2000

Am. J. Respir. Crit. Care Med. 2001; 163: 283-291. [Full text]  

CORRESPONDENCE:

Antonio Duenas-Laita, Santiago Nogué, and Ja-Liang Lin

ERRATUM: CYCLOPHOSPHAMIDE IN PARAQUAT POISONING

Am. J. Respir. Crit. Care Med. 2001; 163: 292. [Full text]  

Valentin Popa, Paul Enright, and Robert Crapo

ATS GUIDELINES FOR METHACHOLINE AND EXERCISE CHALLENGE TESTING

Am. J. Respir. Crit. Care Med. 2001; 163: a292-293. [Full text]  

Richard M. Effros, John Hunt, and Benjamin M. Gaston

ENDOGENOUS AIRWAY ACIDIFICATION: IMPLICATIONS FOR ASTHMA PATHOLOGY

Am. J. Respir. Crit. Care Med. 2001; 163: 293-294. [Full text]  

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