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Contents: Volume 161, Issue 4; April 1, 2000   [Index by Author] 
       EDITORIALS
       UPDATE IN NONPULMONARY CRITICAL CARE
       HOW IT REALLY HAPPENED
       STATE OF THE ART
       Airway Biology and Disease
       Critical Care
       Neuromuscular Control of Breathing and Pulmonary Function Testing
       Pulmonary Fibrosis and Transplantation
       Tuberculosis and Infection
       AMERICAN THORACIC SOCIETY
       CORRESPONDENCE
       Supplement:
"SUPPLEMENT: AMERICAN THORACIC SOCIETY/CENTERS FOR DISEASE CONTROL AND PREVENTION-TARGETED TUBERCULIN TESTING AND TREATMENT OF LATENT TUBERCULOSIS INFECTION"
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EDITORIALS:

Martin J. Tobin
Introducing The "Update in Nonpulmonary Critical Care" Series
Am. J. Respir. Crit. Care Med. 2000; 161: 1069. [Full text]  


UPDATE IN NONPULMONARY CRITICAL CARE:

STEPHEN C. HAMMILL and ROLF D. HUBMAYR
The Rapidly Changing Management of Cardiac Arrhythmias
Am. J. Respir. Crit. Care Med. 2000; 161: 1070-1073. [Full text]  


HOW IT REALLY HAPPENED:

MARY ELLEN AVERY
Surfactant Deficiency in Hyaline Membrane Disease . The Story of Discovery
Am. J. Respir. Crit. Care Med. 2000; 161: 1074-1075. [Full text]  


STATE OF THE ART:

WILLIAM N. ROM, JOHN G. HAY, THEODORE C. LEE, YIXING JIANG, and KAM-MENG TCHOU-WONG
Molecular and Genetic Aspects of Lung Cancer
Am. J. Respir. Crit. Care Med. 2000; 161: 1355-1367. [Full text]  


ARTICLES:

Airway Biology and Disease:

FRANÇOIS FRAISSE, LAURENT HOLZAPFEL, JEAN-MICHEL COULAND, GERALD SIMONNEAU, BERNARD BEDOCK, MARC FEISSEL, PATRICK HERBECQ, REGINALD PORDES, JEAN-FRANÇOIS POUSSEL, LOUIS ROUX, and The Association of Non-University Affiliated Intensive Care Specialist Physicians of France
Nadroparin in the Prevention of Deep Vein Thrombosis in Acute Decompensated COPD
Am. J. Respir. Crit. Care Med. 2000; 161: 1109-1114. [Abstract] [Full text]  

MICHAEL R. LITTNER, JONATHAN S. ILOWITE, DONALD P. TASHKIN, MITCHELL FRIEDMAN, CHARLES W. SERBY, SHAILENDRA S. MENJOGE, and THEODORE J. WITEK, Jr.
Long-Acting Bronchodilation with Once-Daily Dosing of Tiotropium (Spiriva) in Stable Chronic Obstructive Pulmonary Disease
Am. J. Respir. Crit. Care Med. 2000; 161: 1136-1142. [Abstract] [Full text]  

NORIAKI TAKABATAKE, HIDENORI NAKAMURA, SHUICHI ABE, SUMITO INOUE, TOSHIHIKO HINO, HIROSHI SAITO, HIDEKI YUKI, SHUICHI KATO, and HITONOBU TOMOIKE
The Relationship between Chronic Hypoxemia and Activation of the Tumor Necrosis Factor-alpha System in Patients with Chronic Obstructive Pulmonary Disease
Am. J. Respir. Crit. Care Med. 2000; 161: 1179-1184. [Abstract] [Full text]  

CLAUDIA L. ORDOÑEZ, THOMAS E. SHAUGHNESSY, MICHAEL A. MATTHAY, and JOHN V. FAHY
Increased Neutrophil Numbers and IL-8 Levels in Airway Secretions in Acute Severe Asthma . Clinical and Biologic Significance
Am. J. Respir. Crit. Care Med. 2000; 161: 1185-1190. [Abstract] [Full text]  

DENNIS E. NIEWOEHNER, DOROTHEA COLLINS, and MARCIA L.ERBLAND for the Department of  Veterans Affairs Cooperative Study Group
Relation of FEV1 to Clinical Outcomes during Exacerbations of Chronic Obstructive Pulmonary Disease
Am. J. Respir. Crit. Care Med. 2000; 161: 1201-1205. [Abstract] [Full text]  

PHILIP E. SILKOFF, JIMMIE T. SYLVESTER, NOE ZAMEL, and SOLBERT PERMUTT
Airway Nitric Oxide Diffusion in Asthma . Role in Pulmonary Function and Bronchial Responsiveness
Am. J. Respir. Crit. Care Med. 2000; 161: 1218-1228. [Abstract] [Full text]  

JEFFREY D. HASDAY, SUSAN S. MELTZER, WENDY C. MOORE, PETER WISNIEWSKI, J. RICHARD HEBEL, CARMINE LANNI, LOUISE M. DUBÉ, and EUGENE R. BLEECKER
Anti-inflammatory Effects of Zileuton in a Subpopulation of Allergic Asthmatics
Am. J. Respir. Crit. Care Med. 2000; 161: 1229-1236. [Abstract] [Full text]  

AARON DEYKIN, ANTHONY F. MASSARO, ERIN COULSTON, JEFFREY M. DRAZEN, and ELLIOT ISRAEL
Exhaled Nitric Oxide Following Repeated Spirometry or Repeated Plethysmography in Healthy Individuals
Am. J. Respir. Crit. Care Med. 2000; 161: 1237-1240. [Abstract] [Full text]  

MARIE-PIERRE ORYSZCZYN, ISABELLA ANNESI-MAESANO, DENIS CHARPIN, EVELYNE PATY, JEAN MACCARIO, and FRANCINE KAUFFMANN
Relationships of Active and Passive Smoking to Total IgE in Adults of the Epidemiological Study of the Genetics and Environment of Asthma, Bronchial Hyperresponsiveness, and Atopy (EGEA)
Am. J. Respir. Crit. Care Med. 2000; 161: 1241-1246. [Abstract] [Full text]  

PAOLO PAREDI, SERGEI A. KHARITONOV, DAVID LEAK, PALLAV L. SHAH, DEREK CRAMER, MARGARET E. HODSON, and PETER J. BARNES
Exhaled Ethane Is Elevated in Cystic Fibrosis and Correlates with Carbon Monoxide Levels and Airway Obstruction
Am. J. Respir. Crit. Care Med. 2000; 161: 1247-1251. [Abstract] [Full text]  

ALAN H. COHEN, STUART C. SWEET, ERIC MENDELOFF, GEORGE B. MALLORY, Jr., CHARLES B. HUDDLESTON, MADELEINE KRAUS, MICHAEL KELLY, ROBERT HAYASHI, and MICHAEL R. DEBAUN
High Incidence of Posttransplant Lymphoproliferative Disease in Pediatric Patients with Cystic Fibrosis
Am. J. Respir. Crit. Care Med. 2000; 161: 1252-1255. [Abstract] [Full text]  

ROBERT H. BROWN, PIERRE CROISILLE, BEATRICE MUDGE, FIONA B. DIEMER, SOLBERT PERMUTT, and ALKIS TOGIAS
Airway Narrowing in Healthy Humans Inhaling Methacholine without Deep Inspirations Demonstrated by HRCT
Am. J. Respir. Crit. Care Med. 2000; 161: 1256-1263. [Abstract] [Full text]  

KENZO SOEJIMA, KAZUHIRO YAMAGUCHI, EIICHI KOHDA, KEI TAKESHITA, YOKO ITO, HIROAKI MASTUBARA, TSUYOSHI OGUMA, TAKASHI INOUE, YASUYUKI OKUBO, KAZUHISA AMAKAWA, HIROKI TATENO, and TETSUYA SHIOMI
Longitudinal Follow-up Study of Smoking-induced Lung Density Changes by High-resolution Computed Tomography
Am. J. Respir. Crit. Care Med. 2000; 161: 1264-1273. [Abstract] [Full text]  

KAORU HAMADA, CARROLL-ANN GOLDSMITH, ALEJANDRA GOLDMAN, and LESTER KOBZIK
Resistance of Very Young Mice to Inhaled Allergen Sensitization Is Overcome by Coexposure to an Air-Pollutant Aerosol
Am. J. Respir. Crit. Care Med. 2000; 161: 1285-1293. [Abstract] [Full text]  

KENNETH W. T. TSANG, GEORGE TIPOE, JUNE SUN, JAMES C. M. HO, BING LAM, LING ZHENG, GAIK C. OOI, MARY IP, and WAH-KIT LAM
Severe Bronchiectasis in Patients with "Cystlike" Structures within the Ciliary Shafts
Am. J. Respir. Crit. Care Med. 2000; 161: 1300-1305. [Abstract] [Full text]  

TORSTEN UHLIG, JOHANNES H. WILDHABER, NEIL CARROLL, DEBRA J. TURNER, PETER R. GRAY, NIGEL DORE, ALAN L. JAMES, and PETER D. SLY
Pulmonary Vascular Congestion Selectively Potentiates Airway Responsiveness in Piglets
Am. J. Respir. Crit. Care Med. 2000; 161: 1306-1313. [Abstract] [Full text]  

FABRICE BUREAU, GIUSEPPINA BONIZZI, NATHALIE KIRSCHVINK, SYLVIE DELHALLE, DANIEL DESMECHT, MARIE-PAULE MERVILLE, VINCENT BOURS, and PIERRE LEKEUX
Correlation between Nuclear Factor-kappa B Activity in Bronchial Brushing Samples and Lung Dysfunction in an Animal Model of Asthma
Am. J. Respir. Crit. Care Med. 2000; 161: 1314-1321. [Abstract] [Full text]  

PATRICK G. KNOTT, PAUL R. GATER, and CLAUDE P. BERTRAND
Airway Inflammation Driven by Antigen-specific Resident Lung CD4+ T Cells in alpha beta -T Cell Receptor Transgenic Mice
Am. J. Respir. Crit. Care Med. 2000; 161: 1340-1348. [Abstract] [Full text]  


Critical Care:

MICHAEL R. PINSKY and PHILLIPE RICO
Cardiac Contractility Is Not Depressed in Early Canine Endotoxic Shock
Am. J. Respir. Crit. Care Med. 2000; 161: 1087-1093. [Abstract] [Full text]  

ANDREA PURRO, LORENZO APPENDINI, ANDREA DE GAETANO, MARTA GUDJONSDOTTIR, CLAUDIO F. DONNER, and ANDREA ROSSI
Physiologic Determinants of Ventilator Dependence in Long-term Mechanically Ventilated Patients
Am. J. Respir. Crit. Care Med. 2000; 161: 1115-1123. [Abstract] [Full text]  

CAROLINE BEARDSMORE, ISOBEL DUNDAS, KERRY POOLE, KATIE ENOCK, and JANET STOCKS
Respiratory Function in Survivors of the United Kingdom Extracorporeal Membrane Oxygenation Trial
Am. J. Respir. Crit. Care Med. 2000; 161: 1129-1135. [Abstract] [Full text]  

RICHARD H. KALLET, ROBERT M. JASMER, JOHN M. LUCE, LUDWIG H. LIN, and JAMES D. MARKS
The Treatment of Acidosis in Acute Lung Injury with Tris-Hydroxymethyl Aminomethane (THAM)
Am. J. Respir. Crit. Care Med. 2000; 161: 1149-1153. [Abstract] [Full text]  

VANCE G. NIELSEN, MANUEL S. BAIRD, LAN CHEN, and SADIS MATALON
DETANONOate, a Nitric Oxide Donor, Decreases Amiloride-sensitive Alveolar Fluid Clearance in Rabbits
Am. J. Respir. Crit. Care Med. 2000; 161: 1154-1160. [Abstract] [Full text]  

MICHEL DOJAT, ALAIN HARF, DOMINIQUE TOUCHARD, FRANÇOIS LEMAIRE, and LAURENT BROCHARD
Clinical Evaluation of a Computer-controlled Pressure Support Mode
Am. J. Respir. Crit. Care Med. 2000; 161: 1161-1166. [Abstract] [Full text]  

SAMIR JABER, REDOUANE FODIL, ANNALISA CARLUCCI, MOHAMED BOUSSARSAR, JÉRÔME PIGEOT, FRANÇOIS LEMAIRE, ALAIN HARF, FRÉDÉRIC LOFASO, DANIEL ISABEY, and LAURENT BROCHARD
Noninvasive Ventilation with Helium-Oxygen in Acute Exacerbations of Chronic Obstructive Pulmonary Disease
Am. J. Respir. Crit. Care Med. 2000; 161: 1191-1200. [Abstract] [Full text]  

DAVID E. SMITH, GAIL OTULAKOWSKI, HERMAN YEGER, MARTIN POST, ERNST CUTZ, and HUGH M. O'BRODOVICH
Epithelial Na+ Channel (ENaC) Expression in the Developing Normal and Abnormal Human Perinatal Lung
Am. J. Respir. Crit. Care Med. 2000; 161: 1322-1331. [Abstract] [Full text]  


Neuromuscular Control of Breathing and Pulmonary Function Testing:

VINCENZO BELLIA, RICCARDO PISTELLI, FILIPPO CATALANO, RAFFAELE ANTONELLI-INCALZI, VITTORIO GRASSI, GAETANO MELILLO, DARIO OLIVIERI, and FRANCO RENGO
Quality Control of Spirometry in the Elderly . The SA.R.A. Study
Am. J. Respir. Crit. Care Med. 2000; 161: 1094-1100. [Abstract] [Full text]  

BRIAN KOROTZER, SOLITA ONG, and JAMES E. HANSEN
Ethnic Differences in Pulmonary Function in Healthy Nonsmoking Asian-Americans and European-Americans
Am. J. Respir. Crit. Care Med. 2000; 161: 1101-1108. [Abstract] [Full text]  

CHRISTINA M. SPENGLER and STEVEN A. SHEA
Sleep Deprivation Per Se Does Not Decrease the Hypercapnic Ventilatory Response in Humans
Am. J. Respir. Crit. Care Med. 2000; 161: 1124-1128. [Abstract] [Full text]  

JOAQUIM GEA, QUTAYBA HAMID, GUY CZAIKA, ERCHENG ZHU, VID MOHAN-RAM, GEOFFREY GOLDSPINK, and ALEJANDRO GRASSINO
Expression of Myosin Heavy-Chain Isoforms in the Respiratory Muscles Following Inspiratory Resistive Breathing
Am. J. Respir. Crit. Care Med. 2000; 161: 1274-1278. [Abstract] [Full text]  

THEODOROS VASSILAKOPOULOS, ZAFIRIA MASTORA, PARASKEVI KATSAOUNOU, GEORGE DOUKAS, SERAFIM KLIMOPOULOS, CHARIS ROUSSOS, and SPYROS ZAKYNTHINOS
Contribution of Pain to Inspiratory Muscle Dysfunction after Upper Abdominal Surgery . A Randomized Controlled Trial
Am. J. Respir. Crit. Care Med. 2000; 161: 1372-1375. [Abstract] [Full text]  


Pulmonary Fibrosis and Transplantation:

MANI S. KAVURU, EUGENE J. SULLIVAN, RITA PICCIN, MARY JANE THOMASSEN, and JAMES K. STOLLER
Exogenous Granulocyte-Macrophage Colony-Stimulating Factor Administration for Pulmonary Alveolar Proteinosis
Am. J. Respir. Crit. Care Med. 2000; 161: 1143-1148. [Abstract] [Full text]  

WILLIAM W. DOUGLAS, JAY H. RYU, and DARRELL R. SCHROEDER
Idiopathic Pulmonary Fibrosis . Impact of Oxygen and Colchicine, Prednisone, or No Therapy on Survival
Am. J. Respir. Crit. Care Med. 2000; 161: 1172-1178. [Abstract] [Full text]  

WAN C. TAN, DIWEN QIU, BENG L. LIAM, TZE P. NG, SZU H. LEE, STEPHAN F. van EEDEN, YULIA D'YACHKOVA, and JAMES C. HOGG
The Human Bone Marrow Response to Acute Air Pollution Caused by Forest Fires
Am. J. Respir. Crit. Care Med. 2000; 161: 1213-1217. [Abstract] [Full text]  

KOTARO TAMAGAWA, YASUYUKI TAOOKA, AKIHIRO MAEDA, KEIKO HIYAMA, SHINICHI ISHIOKA, and MICHIO YAMAKIDO
Inhibitory Effects of a Lecithinized Superoxide Dismutase on Bleomycin-Induced Pulmonary Fibrosis in Mice
Am. J. Respir. Crit. Care Med. 2000; 161: 1279-1284. [Abstract] [Full text]  

MARTHA SUE CARRAWAY, ANDREW J. GHIO, JACQUELINE D. CARTER, and CLAUDE A. PIANTADOSI
Detection of Granulocyte-Macrophage Colony-Stimulating Factor in Patients with Pulmonary Alveolar Proteinosis
Am. J. Respir. Crit. Care Med. 2000; 161: 1294-1299. [Abstract] [Full text]  

ERKKI A. KALLIO, KARL B. LEMSTRÖM, PEKKA J. HÄYRY, UNA S. RYAN, and PETRI K. KOSKINEN
Blockade of Complement Inhibits Obliterative Bronchiolitis in Rat Tracheal Allografts
Am. J. Respir. Crit. Care Med. 2000; 161: 1332-1339. [Abstract] [Full text]  

COLM T. LEONARD, PAOLA M. SOCCAL, LIANNE SINGER, GERALD J. BERRY, JAMES THEODORE, PATRICK G. HOLT, RAMONA L. DOYLE, and GLENN D. ROSEN
Dendritic Cells and Macrophages in Lung Allografts . A Role in Chronic Rejection?
Am. J. Respir. Crit. Care Med. 2000; 161: 1349-1354. [Abstract] [Full text]  


Tuberculosis and Infection:

ROBERT S. WALLIS, MARK D. PERKINS, MANIJEH PHILLIPS, MOSES JOLOBA, ALICE NAMALE, JOHN L. JOHNSON, CHRISTOPHER C. WHALEN, LUCILEIA TEIXEIRA, BARBARA DEMCHUK, REYNALDO DIETZE, ROY D. MUGERWA, KATHLEEN EISENACH, and JERROLD J. ELLNER
Predicting the Outcome of Therapy for Pulmonary Tuberculosis
Am. J. Respir. Crit. Care Med. 2000; 161: 1076-1080. [Abstract] [Full text]  

AHSAN M. AROZULLAH, PAUL R. YARNOLD, ROBERT A. WEINSTEIN, NDUKA NWADIARO, THOMAS B. MCILRAITH, JOAN S. CHMIEL, ALISON M. SIPLER, CHEELING CHAN, MATTHEW B. GOETZ, DAVID N. SCHWARTZ, and CHARLES L. BENNETT
A New Preadmission Staging System for Predicting Inpatient Mortality from HIV-associated Pneumocystis carinii Pneumonia in the Early Highly Active Antiretroviral Therapy (HAART) Era
Am. J. Respir. Crit. Care Med. 2000; 161: 1081-1086. [Abstract] [Full text]  

MARGARITA E. VILLARINO, MICHAEL J. BRENNAN, CHARLES M. NOLAN, ANTONINO CATANZARO, LINDA L. LUNDERGAN, NAOMI N. BOCK, CRYSTAL L. JONES, YONG-CHEN WANG, and WILLIAM J. BURMAN
Comparison Testing of Current (PPD-S1) and Proposed (PPD-S2) Reference Tuberculin Standards
Am. J. Respir. Crit. Care Med. 2000; 161: 1167-1171. [Abstract] [Full text]  

SHAWN D. AARON, WENDY FERRIS, DEBORAH A. HENRY, DAVID P. SPEERT, and NONI E. MACDONALD
Multiple Combination Bactericidal Antibiotic Testing for Patients with Cystic Fibrosis Infected with Burkholderia cepacia
Am. J. Respir. Crit. Care Med. 2000; 161: 1206-1212. [Abstract] [Full text]  

KEISHI KUBO, YOSHITAKA YAMAZAKI, MASAYUKI HANAOKA, HIROSHI NOMURA, KEISAKU FUJIMOTO, TAKAYUKI HONDA, MASAO OTA, and YOSHIMASA KAMIJOU
Analysis of HLA Antigens in Mycobacterium avium-intracellulare Pulmonary Infection
Am. J. Respir. Crit. Care Med. 2000; 161: 1368-1371. [Abstract] [Full text]  


AMERICAN THORACIC SOCIETY:

Diagnostic Standards and Classification of Tuberculosis in Adults and Children . This Official Statement of the American Thoracic Society and the Centers for Disease Control and Prevention was Adopted by the ATS Board of Directors, July 1999. This Statement was endorsed by the Council of the Infectious Disease Society of America, September 1999 
Am. J. Respir. Crit. Care Med. 2000; 161: 1376-1395. [Full text]  


CORRESPONDENCE:

STEPHEN J. JAY and PAUL ENRIGHT
REFERENCE EQUATIONS FOR THE SIX-MINUTE WALK IN HEALTHY ADULTS
Am. J. Respir. Crit. Care Med. 2000; 161: 1396. [Full text]  

J. J. ROUBY
A LUNG COMPUTED TOMOGRAPHIC ASSESSMENT OF POSITIVE END-EXPIRATORY PRESSURE- INDUCED LUNG OVERDISTENSION
Am. J. Respir. Crit. Care Med. 2000; 161: 1396a-1397. [Full text]  

GUSTAVO J. RODRIGO, CARLOS RODRIGO, MICHAEL A. JANTZ, and STEVEN A. SAHN
CORTICOSTEROIDS IN ACUTE RESPIRATORY FUNCTION
Am. J. Respir. Crit. Care Med. 2000; 161: 1397-1398. [Full text]  


SUPPLEMENT: "SUPPLEMENT: AMERICAN THORACIC SOCIETY/CENTERS FOR DISEASE CONTROL AND PREVENTION-TARGETED TUBERCULIN TESTING AND TREATMENT OF LATENT TUBERCULOSIS INFECTION"

Targeted Tuberculin Testing and Treatment of Latent Tuberculosis Infection . This Official Statement of the American Thoracic Society was adopted by the ATS Board of Directors, July 1999. This is a Joint Statement of the American Thoracic Society (ATS) and the Centers for Disease Control and Prevention (CDC). This Statement was endorsed by the Council of the Infectious Diseases Society of America (IDSA), September 1999, and the sections of this Statement as it relates to infants and children were endorsed by the American Academy of Pediatrics (AAP), August 1999.
Am. J. Respir. Crit. Care Med. 2000; 161: 221S-247. [Full text] [Online Data Supplement]  


To see an article, click its [Full Text] link. To review more than one abstract at a time, check the boxes to the left of the titles you want, and click the "Get All Checked Abstract(s)" button. To see one abstract at a time, click its [Abstract] link.


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