Published ahead of print on April 26, 2007, doi:10.1164/rccm.200607-883OC Am. J. Respir. Crit. Care Med., Volume 176, Number 2, July 2007, 174-180 A more recent version of this article appeared on July 15, 2007
Submitted on July 1, 2006 Standard Reference for the 6-minute Walk Test in Healthy Children Aged 7 to 16 YearsAlbert M Li1*,1 Department of Pediatrics, The Chinese University of Hong Kong, Shatin, Hong Kong, 2 Centre for Epidemiology and Biostatistics, The Chinese University of Hong Kong, Shatin, Hong Kong * To whom correspondence should be addressed. E-mail: albertmli{at}cuhk.edu.hk.
Objective: To construct height-specific standards of six-minute walk test (6MWT) for children aged 7 to 16 years. Design: A prospective cross sectional study. Methods: The anthropometric data, spirometric lung function and six-minute walk distance (6MWD) of Chinese children aged 7 to 16 years were prospectively measured using standardized protocols. The findings were used to construct height-specific standards of 6MWT. The LMS method using maximum penalised likelihood was used to facilitate model fitting. Factors significantly associated with 6MWD were also determined. Results: From January 2005 to April 2006, a total of 1,445 subjects were studied. The measured variables showed a normal distribution. Height-specific reference standards for 6MWT were constructed for both male and female children. Forward stepwise multiple regression analysis revealed height and difference in heart rate before and after the walk test to be important clinical variables associated with 6MWD. Conclusion: These 6MWD standards will provide useful references for the care of pediatric patients. Key words: 6-minute walk test, child, reference curves
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