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Published ahead of print on June 23, 2005, doi:10.1164/rccm.200502-259OC

Am. J. Respir. Crit. Care Med., Volume 172, Number 7, October 2005, 842-847

A more recent version of this article appeared on October 1, 2005
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Submitted on February 17, 2005
Accepted on June 16, 2005

Prevalence of Chronic Obstructive Pulmonary Disease in Korea: A Population-based Spirometry Survey

Dong Soon Kim1*, Young Sam Kim1, Kee Suk Chung1, Jung Hyun Chang1, Chae-Man Lim1, Jae Ho Lee1, Soo-Taek Uh1, Jae Jeong Shim1, and Woo Jin Lew1

1 Korean Academy of Tuberculosis and Respiratory Diseases, Seoul, Korea, Republic of

* To whom correspondence should be addressed. E-mail: dskim{at}amc.seoul.kr.

Rationale. Although chronic obstructive pulmonary disease is a leading cause of mortality and morbidity worldwide, there are only limited data on the prevalence, especially in Asia. Objectives. A population-based epidemiological survey of chronic obstructive pulmonary disease in a representative national sample was conducted using spirometry. Methods. A stratified multistage clustered probability design was used to select a nationally representative sample. The survey was performed in conjunction with the 2nd Korean National, Health and Nutritional Examination Survey of 9,243 adults over the age of 18 years. The participation rate was 88.8% for questionnaires and 52.1% for spirometry. Results: The prevalence of chronic obstructive pulmonary disease using Global Initiative for Obstructive Lung Disease criteria (a ratio of forced expiratory volume in one second to forced vital capacity of less than 0.7) was 17.2% (25.8 %: men, 9.6 %:women) among the subjects older than 45 years. In the adults of all ages (age> 18 years), the prevalence of airway obstruction was 7.8% (10.9 % in men, 4.9 % in women). The majority of these were found to be mild in degree, and only a minority of these subjects had received physician diagnosis or treatment. Multivariate analysis revealed that age over 65 years, male gender, smoking more than 20 pack-years and low income were independent predictors for chronic obstructive pulmonary disease. Conclusions. Seventeen percent of Korean adults over the age of 45 years have mild chronic obstructive pulmonary disease.
Key words: National prevalence, COPD, spirometry, population based survey, smoking




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