Published ahead of print on September 3, 2004, doi:10.1164/rccm.200404-519OC
Am. J. Respir. Crit. Care Med., Volume 170, Number 10, November 2004, 1108-1113
A more recent version of this article appeared on November 15, 2004
Submitted on April 20, 2004
Accepted on August 28, 2004
Prevalence of Sleep Disordered Breathing in Middle-aged Korean Men and Women
JinKwan Kim1, KwangHo In2, JeHyeong Kim2, SeHwa You2, KyungHo Kang2, JaeJeong Shim2, SangYeub Lee2, JungBok Lee3, SeungGwan Lee4, Chan Park5, and Chol Shin6*
1 Pulmonary Sleep Disorder Center, Ansan Hospital, Korea University Medical Center, Ansan, Gyeonggi-do, Republic of Korea,
2 Division of Pulmonary, Department of Internal Medicine, Korea University Medical Center, Seungbuk-gu, Seoul, Republic of Korea,
3 Department of Statistics, Korea University, Seungbuk-gu, Seoul, Republic of Korea,
4 Department of Clinical Laboratory Science, Korea University, Seungbuk-gu, Seoul, Republic of Korea,
5 Division of Epidemiology and Bioinformatics, National Genome Research Institute, National Institute of Health, Korea Center for Disease Control and Prevention, Eyunpyung-gu, Seoul, Republic of Korea,
6 Division of Pulmonary, Department of Internal Medicine, Korea University Medical Center, Seungbuk-gu, Seoul, Republic of Korea; Pulmonary Sleep Disorder Center, Ansan Hospital, Korea University Medical Center, Ansan, Gyeonggi-do, Republic of Korea; Institutes of Human Genomic Study, Ansan Hospital, Korea University Medical Center, Ansan, Gyeonggi-do, Republic of Korea
* To whom correspondence should be addressed. E-mail: chol-shin{at}korea.ac.kr.
With many epidemiologic studies made to establish the prevalence of sleep disordered breathing and obstructive sleep apnea syndrome in western countries, no such data have been reported in Korea. The purpose of this study was to examine the prevalence of the sleep disordered breathing and the obstructive sleep apnea syndrome, and their related factors in Korean adults aged 40-69 years. Among the total of 5020 participants at the baseline examination of the Korean Health and Genome Study, a random sample of 457 men and women was studied with employment of the overnight full polysomnography to determine the prevalence of SDB and OSAS. The prevalence of SDB (apnea-hypopnea index 5) was 27% and 16% in men and women, respectively. When OSAS was defined by an apnea-hypopnea index 5 plus excessive daytime sleepiness, its prevalence was 4.5% in men and 3.2% in women. Logistic regression analyses showed that gender, body mass index, and hypertension were closely associated with the risk of SDB. Our findings show that SDB is a common problem in Korean adult population. Understanding and treatment of sleep disordered breathing may be essential in terms of intervention to reduce the risk of related medical problems.
Key words: sleep apnea, Epidemiology, Korea
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