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Published ahead of print on November 12, 2004, doi:10.1164/rccm.200404-513OC

Am. J. Respir. Crit. Care Med., Volume 171, Number 3, February 2005, 257-260

A more recent version of this article appeared on February 1, 2005
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Submitted on April 18, 2004
Accepted on November 10, 2004

Prospective Surveillance for Pseudomonas aeruginosa Cross-infection at a Cystic Fibrosis Centre

Andrew M Jones1*, Mary E Dodd1, John RW Govan2, Catherine J Doherty2, Catherine M Smith1, Barbara J Isalska3, and A Kevin Webb1

1 Adult Cystic Fibrosis Centre, South Manchester University Hospitals, Wythenshawe Hospital, Manchester, United Kingdom, 2 Department of Medical Microbiology, University of Edinburgh, Edinburgh, United Kingdom, 3 Department of Medical Microbiology, South Manchester University Hospitals NHS Trust, Wythenshawe Hospital, Manchester, United Kingdom

* To whom correspondence should be addressed. E-mail: andmarkj{at}hotmail.com.

We have performed a 4-year prospective surveillance for Pseudomonas aeruginosa cross-infection at a large regional adult cystic fibrosis centre. Despite purpose built facilities in a new building and the practise of strict hygiene, P. aeruginosa cross-infection has continued. In contrast, individuals segregated from the cohort of patients with chronic P. aeruginosa infection but who attend the same centre have not acquired infection with transmissible P. aeruginosa strains. Simple infection control measures alone do not prevent the spread of transmissible P. aeruginosa strains between individuals with cystic fibrosis . However, in our clinic patient segregation effectively controlled spread of such strains.


Key words: cystic fibrosis; Pseudomonas aeruginosa; cross-infection; infection control; incidence




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