help button home button
AJRCCM
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH
Published ahead of print on April 29, 2004, doi:10.1164/rccm.200306-789OC

Am. J. Respir. Crit. Care Med., Volume 170, Number 3, August 2004, 279-287

A more recent version of this article appeared on August 1, 2004
This Article
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
200306-789OCv1
170/3/279    most recent
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Butler, L. M
Right arrow Articles by London, S. J
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Butler, L. M
Right arrow Articles by London, S. J

Submitted on June 15, 2003
Accepted on April 28, 2004

Dietary Fiber and Reduced Cough with Phlegm: A Cohort Study in Singapore

Lesley M Butler1*, Woon-Puay Koh2, Hin-Peng Lee3, Mimi C Yu2, and Stephanie J London1

1 Epidemiology Branch, Department of Health and Human Services, National Institute of Environmental Health Sciences and National Institutes of Health, Research Triangle Park, NC, USA, 2 Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA, USA, 3 National University of Singapore, Singapore

* To whom correspondence should be addressed. E-mail: lmbutler{at}ucdavis.edu.

Smoking is the major risk factor for chronic respiratory symptoms, but dietary factors may also play a role. Most studies of diet and lung disease have been cross-sectional and conducted in populations with a Western-style diet. We analyzed the relation between dietary intake at baseline and new onset of cough with phlegm in a population-based cohort of 63,257 middle-aged Chinese men and women initiated in Singapore between 1993 and 1998. Beginning in 1999, we ascertained respiratory symptoms by telephone interview and have identified 571 incident cases of cough with phlegm among the 49,140 cohort members with completed follow-up. Non-starch polysaccharides (NSP), a major component of dietary fiber, total fruit and soy isoflavones had the strongest associations. Odds ratios comparing highest to lowest quartiles after adjustment for age, gender, dialect group, total energy intake and smoking were 0.61 (95% CI:0.47, 0.78, P for trend <0.001) for NSP, 0.67 (95% CI: 0.52, 0.87, P for trend=0.006) for fruit and 0.67 (95% CI:0.53, 0.86, P for trend=0.001) for soy isoflavones. These data suggest that a diet high in fiber from fruit and, possibly, soyfoods may reduce the incidence of chronic respiratory symptoms. Associated nutrients, such as flavonoids, may contribute to this association.
Key words: dietary fiber, soy, fruit, chronic bronchitis, COPD




This article has been cited by other articles:


Home page
 Am J EpidemiolHome page
H. Kan, J. Stevens, G. Heiss, K. M. Rose, and S. J. London
Dietary Fiber, Lung Function, and Chronic Obstructive Pulmonary Disease in the Atherosclerosis Risk in Communities Study
Am. J. Epidemiol., March 1, 2008; 167(5): 570 - 578.
[Abstract] [Full Text] [PDF]

Home page
 ThoraxHome page
R. Varraso, T. T Fung, F. B Hu, W. Willett, and C. A Camargo
Prospective study of dietary patterns and chronic obstructive pulmonary disease among US men
Thorax, September 1, 2007; 62(9): 786 - 791.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
L. M. Butler, W.-P. Koh, H.-P. Lee, M. Tseng, M. C. Yu, and S. J. London
On Previous Findings Concerning Preserved Meat Intake and Respiratory Disease
Am. J. Respir. Crit. Care Med., August 1, 2007; 176(3): 315 - 315.
[Full Text] [PDF]

Home page
 Proc Am Thorac SocHome page
S. J. London
Gene-Air Pollution Interactions in Asthma
Proceedings of the ATS, July 1, 2007; 4(3): 217 - 220.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
J. S. Burns, D. W. Dockery, L. M. Neas, J. Schwartz, B. A. Coull, M. Raizenne, and F. E. Speizer
Low Dietary Nutrient Intakes and Respiratory Health in Adolescents
Chest, July 1, 2007; 132(1): 238 - 245.
[Abstract] [Full Text] [PDF]

Home page
 Am J EpidemiolHome page
T. D. LeVan, W.-P. Koh, H.-P. Lee, D. Koh, M. C. Yu, and S. J. London
Vapor, Dust, and Smoke Exposure in Relation to Adult-Onset Asthma and Chronic Respiratory Symptoms: The Singapore Chinese Health Study
Am. J. Epidemiol., June 15, 2006; 163(12): 1118 - 1128.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
L. M. Butler, W.-P. Koh, H.-P. Lee, M. Tseng, M. C. Yu, and S. J. London
Prospective Study of Dietary Patterns and Persistent Cough with Phlegm among Chinese Singaporeans
Am. J. Respir. Crit. Care Med., February 1, 2006; 173(3): 264 - 270.
[Abstract] [Full Text] [PDF]

Home page
 ThoraxHome page
G L David, W-P Koh, H-P Lee, M C Yu, and S J London
Childhood exposure to environmental tobacco smoke and chronic respiratory symptoms in non-smoking adults: The Singapore Chinese Health Study
Thorax, December 1, 2005; 60(12): 1052 - 1058.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
B. Nemery, W. W. Yew, R. Albert, C. Brun-Buisson, W. MacNee, F. J. Martinez, D. C. Angus, and E. Abraham
Tuberculosis, Nontuberculous Lung Infection, Pleural Disorders, Pulmonary Function, Respiratory Muscles, Occupational Lung Disease, Pulmonary Infections, and Social Issues in AJRCCM in 2004
Am. J. Respir. Crit. Care Med., March 15, 2005; 171(6): 554 - 562.
[Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH
Proc. Am. Thorac. Soc. Am. J. Respir. Cell Mol. Biol.
Copyright © 2004 American Thoracic Society 		  ATS State of the Art Course 2008