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Published ahead of print on November 6, 2003, doi:10.1164/rccm.200302-265OC
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American Journal of Respiratory and Critical Care Medicine Vol 169. pp. 168-173, (2004)
© 2004 American Thoracic Society

Prevalence of Sleep-disordered Breathing and Sleep Apnea in Middle-aged Urban Indian Men

Zarir F. Udwadia, Amita V. Doshi, Sharmila G. Lonkar and Chandrajeet I. Singh

Department of Chest Medicine, P. D. Hinduja National Hospital and Medical Research Centre, Veer Savarkar Marg, Mahim, Mumbai, India

Correspondence and requests for reprints should be addressed to Zarir F. Udwadia, M.D., F.R.C.P., F.C.C.P., Department of Chest Medicine, P. D. Hinduja National Hospital and Medical Research Centre, Veer Savarkar Marg, Mahim, Mumbai 400002, Maharashtra, India. E-mail: zfu{at}vsnl.com

No data are available on the prevalence of sleep-disordered breathing (SDB) and obstructive sleep apnea–hypopnea syndrome (OSAHS) in Indians. We conducted a two-phase cross-sectional prevalence study for the same in healthy urban Indian males (35–65 years) coming to our hospital in Bombay for a routine health check. We also investigated its risk factors and evaluated the significance of the most commonly asked questions that best correlated with the presence of OSAHS. In the first phase, 658 subjects (94%) returned completed questionnaires regarding their sleep habits and associated medical conditions. In the second phase, 250 of these underwent an overnight home sleep study. The estimated prevalence of SDB (apnea–hypopnea index of 5 or more) was 19.5%, and that of OSAHS (SDB with daytime hypersomnolence) was 7.5%. Multiple stepwise logistic regression determined body mass index, neck girth, and history of diabetes mellitus as the principal covariates of SDB. The presence of snoring, nocturnal choking, unrefreshing sleep, recurrent awakening from sleep, daytime hypersomnolence, and daytime fatigue was each statistically significant for identifying patients with OSAHS. The higher prevalence of OSAHS in urban Indian men is striking and may have major public health implications in a developing country.

Key Words: epidemiology • sleep study • India




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