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Online Data Supplement to Liver-Lung Interactions Following E. coli Bacteremic Sepsis and Secondary Hepatic Ischemia/Reperfusion Injury


Figure E1. Representative photomicrographs of CAE-stained ischemic liver sections obtained from animals at t = 195 min after bacteremic infection with 109 E. coli serotype O55:B5 or infusion of 0.9% NaCl at t = 0, with and without subsequent liver ischemia and brief (1-h) reperfusion. (a) EC + I/R; (b) EC + Sham; (c) NS + I/R; (d) NS + Sham. Images were obtained using Tri-X Kodak film without filtration at a nominal magnification of x 100. Arrows designate polymorphonuclear leukocytes; asterisks designate vacuoles. Bar = 50 :m.

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Figure E2. Mean values (± SEM) for organ W/D ratios after bacteremic infection with 109 E. coli serotype O55:B5 (EC) or infusion of 0.9% NaCl (NS) at t = 0, with and without subsequent liver ischemia and brief (1-h) reperfusion. *p < 0.05 EC + I/R versus cecal W/D values of EC + Sham, NS + I/R, and NS + Sham groups.

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Figure E3. Mean values (± SEM) for organ W/D ratios after bacteremic infection with 109 E. coli serotype O55:B5 or infusion of 0.9% NaCl at t = 0, with and without subsequent liver ischemia and longer-term (24-h) reperfusion. *p < 0.05 versus lung W/D values of EC + Sham, NS + I/R, and NS + Sham groups.

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Figure E4. Mean values (± SEM) for rectal temperature after bacteremic infection with 109 E. coli serotype O55:B5 or infusion of 0.9% NaCl at t = 0, with and without subsequent liver ischemia and longer-term (24-h) reperfusion. There were no significant intergroup differences.

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Figure E5. Mean values (± SEM) for mean arterial pressure after bacteremic infection with 109 E. coli serotype O55:B5 or infusion of 0.9% NaCl at t = 0, with and without subsequent liver ischemia and longer-term (24-h) reperfusion. There were no significant intergroup differences.

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Figure E6. Mean values (± SEM) for pulse rate after bacteremic infection with 109 E. coli serotype O55:B5 or infusion of 0.9% NaCl at t = 0, with and without subsequent liver ischemia and long-term (24-h) reperfusion. There were no significant intergroup differences.

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Figure E7. Mean values (± SEM) for respiratory frequency after bacteremic infection with 109 E. coli serotype O55:B5 or infusion of 0.9% NaCl at t = 0, with and without subsequent liver ischemia and longer-term (24-h) reperfusion. *p < 0.05 versus within-group baseline value; Hp < 0.05 versus time-matched NS + Sham value.

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HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Proc. Am. Thorac. Soc. Am. J. Respir. Cell Mol. Biol.
Copyright © 2008 American Thoracic Society