help button home button
AJRCCM
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Published ahead of print on January 8, 2009, doi:10.1164/rccm.200809-1394CP
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
200809-1394CPv1
179/6/434    most recent
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Lawrence, K. L.
Right arrow Articles by Kollef, M. H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Lawrence, K. L.
Right arrow Articles by Kollef, M. H.
American Journal of Respiratory and Critical Care Medicine Vol 179. pp. 434-438, (2009)
© 2009 American Thoracic Society
doi: 10.1164/rccm.200809-1394CP

Critical Care Perspective

Antimicrobial Stewardship in the Intensive Care Unit

Advances and Obstacles

Kevin L. Lawrence1 and Marin H. Kollef1

1 Department of Medicine, Washington University in St. Louis School of Medicine, St. Louis, Missouri

Correspondence and requests for reprints should be addressed to Marin H. Kollef, M.D., 660 South Euclid, Campus Box 8052, St. Louis, MO 63110. E-mail: mkollef{at}im.wustl.edu

ABSTRACT

Antimicrobial stewardship involves a multifaceted approach that strives to combat the emergence of resistance, improve clinical outcomes, and control costs by improving antimicrobial use. Therefore, stewardship is of great importance and relevance in the intensive care unit. Clinical decision support systems, biomarker-derived treatment algorithms, and improved knowledge regarding the different components of antimicrobial therapy represent some of the advances that have been made in stewardship. Yet, significant obstacles have prevented the full achievement of stewardship's goals, and approaches to confronting these obstacles should be appreciated. Clinicians should realize that antimicrobials are important therapeutic agents and strive to use them wisely.

Key Words: antiinfective agents • biological markers • infection • therapeutics




This article has been cited by other articles:


Home page
 Am. J. Respir. Crit. Care Med.Home page
L. Pagani
Antimicrobial Stewardship: There's No Such Thing as Too Much
Am. J. Respir. Crit. Care Med., January 1, 2010; 181(1): 94 - 94.
[Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Proc. Am. Thorac. Soc. Am. J. Respir. Cell Mol. Biol.
Copyright © 2009 American Thoracic Society 		  Membership Renewal