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Published ahead of print on October 12, 2006, doi:10.1164/rccm.200604-577OC
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American Journal of Respiratory and Critical Care Medicine Vol 175. pp. 55-61, (2007)
© 2007 American Thoracic Society
doi: 10.1164/rccm.200604-577OC


Original Article

Elevated Morbidity and Health Care Use in Children with Obstructive Sleep Apnea Syndrome

Ariel Tarasiuk, Sari Greenberg-Dotan, Tzahit Simon-Tuval, Bruria Freidman, Aviv D. Goldbart, Asher Tal and Haim Reuveni

Sleep-Wake Disorders Unit, and Department of Pediatrics B, Faculty of Health Sciences, Soroka Medical Center, and Departments of Physiology, Epidemiology, and Health Systems Management, Faculty of Health Sciences, and Department of Economics, Faculty of Humanities and Social Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel

Correspondence and requests for reprints should be addressed to Ariel Tarasiuk, Ph.D., Department of Physiology, Faculty of Health Sciences, P.O. Box 653, Ben-Gurion University of the Negev, Beer-Sheva, Israel 84105. E-mail: tarasiuk{at}bgu.ac.il

Rationale: Health care use, a reliable measure of morbidity, is noticeably higher 1 yr before obstructive sleep apnea syndrome (OSAS) diagnosis in preschool children. It is not clear at what age OSAS-related morbidity becomes expressed.

Objective: To explore morbidity and health care use among children with OSAS starting from first year of life.

Methods: Case-control study, starting from the first year of life to date of OSAS diagnosis, among 156 patients (age range, 3–5 yr) and their pair-matched healthy control subjects, by age, sex, primary care physician, and geographic location.

Measurements: Patients with OSAS underwent nocturnal polysomnography studies. Medical records during hospital visits were reviewed for diagnosis. Variables of health care use were obtained from computerized databases of Clalit Health Care Services, the largest health maintenance organization in Israel.

Main Results: From the first year of life to date of OSAS diagnosis, children with OSAS had 40% more (p = 0.048) hospital visits, 20% more repeated (two or more) visits (p < 0.0001), and higher consumption of antiinfective and respiratory system drugs (p < 0.0001). Referrals of children with OSAS to otolaryngology surgeons and pediatric pulmonologists were higher from Year 1 (p < 0.0001) to date of OSAS diagnosis, especially in Year 4 (odds ratio, 9.4; 95% confidence interval, 4.2–21.1). The 215% elevation (p < 0.0001) in health care use of the OSAS group was due mainly to higher occurrence of respiratory tract morbidity (p < 0.0001).

Conclusions: Practitioners should be aware that starting in Year 1 until date of diagnosis, children with OSAS have higher health care use, mostly related to respiratory diseases.

Key Words: children • respiratory tract morbidity • heath care use • obstructive sleep apnea syndrome


AT A GLANCE COMMENTARY

Scientific Knowledge on the Subject
Little is known regarding health care consumption and morbidity among children with obstructive sleep apnea syndrome (OSAS) from the first year of life.

What This Study Adds to the Field
Children with OSAS have higher morbidity and health care use starting from the first year of life. This study suggests the need for early diagnosis and intervention.

 



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