help button home button
AJRCCM
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by MINEO, T. C.
Right arrow Articles by MAGLIOCCHETTI, N.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by MINEO, T. C.
Right arrow Articles by MAGLIOCCHETTI, N.

Am. J. Respir. Crit. Care Med., Volume 165, Number 4, February 2002, 489-494

Effect of Lung Volume Reduction Surgery for Severe Emphysema on Right Ventricular Function

TOMMASO C. MINEO, EUGENIO POMPEO, PAOLA ROGLIANI, MARIO DAURI, FRANCO TURANI, PATRIZIO BOLLERO, and NATALIA MAGLIOCCHETTI, for the Pulmonary Emphysema Research Group

Divisions of Thoracic Surgery, Pulmonary Medicine, and Anesthesiology and Intensive Care Medicine, University Tor Vergata, Rome, Italy

Lung volume reduction surgery (LVRS) can improve the functional capacity of selected patients with severe emphysema. Hypothesized physiologic effects of LVRS include an improvement in right ventricular function, although this has not been investigated in detail. To help clarify this issue, we used fast-thermistor thermodilution at rest and during submaximal upright exercise in 12 patients, before and 6 mo after bilateral LVRS. Preoperatively, all patients had severe airflow obstruction, with a mean FEV1 of 0.69 L and an RV-to-TLC ratio of 0.67. Six months after LVRS, significant improvements occurred in respiratory function measures (+0.39 L in FEV1, p < 0.002; and -0.15 in RV/TLC ratio, p < 0.002) and in right ventricular function indexes measured at rest (+0.21 L in cardiac index [CI], p < 0.01; and +3.0 ml in stroke volume, p < 0.01) and during exercise (+0.9 L in CI, p < 0.002; +10.0 ml in stroke volume index, p < 0.002; and +20% in ejection fraction [EF], p < 0.002). A significant correlation was found between pre- to postoperative changes in the EF response to exercise and changes in the RV/TLC ratio (R = -0.68; p = 0.01). We conclude that a significant improvement in right ventricular performance, particularly during exercise, can occur 6 mo after bilateral LVRS.




This article has been cited by other articles:


Home page
 Proc Am Thorac SocHome page
N. W. Brister, R. E. Barnette, V. Kim, and M. Keresztury
Anesthetic Considerations in Candidates for Lung Volume Reduction Surgery
Proceedings of the ATS, May 1, 2008; 5(4): 432 - 437.
[Abstract] [Full Text] [PDF]

Home page
 Proc Am Thorac SocHome page
J. A. Falk, S. Kadiev, G. J. Criner, S. M. Scharf, O. A. Minai, and P. Diaz
Cardiac Disease in Chronic Obstructive Pulmonary Disease
Proceedings of the ATS, May 1, 2008; 5(4): 543 - 548.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
F. Tacconi, E. Pompeo, D. Forcella, M. Marino, D. Varvaras, and T. C. Mineo
Lung Volume Reduction Reoperations
Ann. Thorac. Surg., April 1, 2008; 85(4): 1171 - 1177.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
J. A. Falk, U. J. Martin, S. Scharf, and G. J. Criner
Lung Elastic Recoil Does Not Correlate With Pulmonary Hemodynamics in Severe Emphysema
Chest, November 1, 2007; 132(5): 1476 - 1484.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
G. J. Criner, S. M. Scharf, J. A. Falk, J. P. Gaughan, A. L. Sternberg, N. B. Patel, H. E. Fessler, O. A. Minai, A. P. Fishman, and for the National Emphysema Treatment Trial Researc
Effect of Lung Volume Reduction Surgery on Resting Pulmonary Hemodynamics in Severe Emphysema
Am. J. Respir. Crit. Care Med., August 1, 2007; 176(3): 253 - 260.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
R. Neviere, M. Catto, N. Bautin, S. Robin, H. Porte, J. Desbordes, and R. Matran
Longitudinal changes in hyperinflation parameters and exercise capacity after giant bullous emphysema surgery.
J. Thorac. Cardiovasc. Surg., November 1, 2006; 132(5): 1203 - 1207.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
T. C. Mineo, V. Ambrogi, D. Mineo, A. Fabbri, E. Fabbrini, and R. Massoud
Bone Mineral Density Improvement After Lung Volume Reduction Surgery for Severe Emphysema
Chest, June 1, 2005; 127(6): 1960 - 1966.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
N. S. Hopkinson, T. P. Toma, D. M. Hansell, P. Goldstraw, J. Moxham, D. M. Geddes, and M. I. Polkey
Effect of Bronchoscopic Lung Volume Reduction on Dynamic Hyperinflation and Exercise in Emphysema
Am. J. Respir. Crit. Care Med., March 1, 2005; 171(5): 453 - 460.
[Abstract] [Full Text] [PDF]

Home page
 Anesth. Analg.Home page
J. E. Hillier, T. P. Toma, and C. E. Gillbe
Bronchoscopic Lung Volume Reduction in Patients with Severe Emphysema: Anesthetic Management
Anesth. Analg., December 1, 2004; 99(6): 1610 - 1614.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
F. Laghi, A. Jubran, A. Topeli, P. J. Fahey, E. R. Garrity Jr, D. J. de Pinto, and M. J. Tobin
Effect of Lung Volume Reduction Surgery on Diaphragmatic Neuromechanical Coupling At 2 Years
Chest, June 1, 2004; 125(6): 2188 - 2195.
[Abstract] [Full Text] [PDF]

Home page
 Eur Respir JHome page
T.C. Mineo, V. Ambrogi, E. Pompeo, S. Elia, D. Mineo, P. Bollero, and I. Nofroni
Impact of lung volume reduction surgery versus rehabilitation on quality of life
Eur. Respir. J., February 1, 2004; 23(2): 275 - 280.
[Abstract] [Full Text] [PDF]

Home page
 Eur Respir JHome page
M. Decramer
Treatment of chronic respiratory failure: lung volume reduction surgery versus rehabilitation
Eur. Respir. J., November 16, 2003; 22(47_suppl): 47S - 56s.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
K. Jorgensen, E. Houltz, U. Westfelt, F. Nilsson, H. Schersten, and S.-E. Ricksten
Effects of Lung Volume Reduction Surgery on Left Ventricular Diastolic Filling and Dimensions in Patients With Severe Emphysema
Chest, November 1, 2003; 124(5): 1863 - 1870.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
F. Laghi and M. J. Tobin
Disorders of the Respiratory Muscles
Am. J. Respir. Crit. Care Med., July 1, 2003; 168(1): 10 - 48.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
M. J. Tobin
Chronic Obstructive Pulmonary Disease, Pollution, Pulmonary Vascular Disease, Transplantation, Pleural Disease, and Lung Cancer in AJRCCM 2002
Am. J. Respir. Crit. Care Med., February 1, 2003; 167(3): 356 - 370.
[Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
ATS/ACCP Statement on Cardiopulmonary Exercise Testing
Am. J. Respir. Crit. Care Med., January 15, 2003; 167(2): 211 - 277.
[Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Proc. Am. Thorac. Soc. Am. J. Respir. Cell Mol. Biol.
Copyright © 2002 American Thoracic Society