Am. J. Respir. Crit. Care Med.,
Volume 163, Number 2, February 2001, 517-523
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J.-A. Park and D. J. Tschumperlin Chronic Intermittent Mechanical Stress Increases MUC5AC Protein Expression Am. J. Respir. Cell Mol. Biol., October 1, 2009; 41(4): 459 - 466. [Abstract] [Full Text] [PDF] |
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S.-W. Park, C. Verhaeghe, L. T. Nguyenvu, R. Barbeau, C. J. Eisley, Y. Nakagami, X. Huang, P. G. Woodruff, J. V. Fahy, and D. J. Erle Distinct Roles of FOXA2 and FOXA3 in Allergic Airway Disease and Asthma Am. J. Respir. Crit. Care Med., October 1, 2009; 180(7): 603 - 610. [Abstract] [Full Text] [PDF] |
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P. Camateros, C. Kanagaratham, J. Henri, R. Sladek, T. J. Hudson, and D. Radzioch Modulation of the allergic asthma transcriptome following resiquimod treatment Physiol Genomics, August 7, 2009; 38(3): 303 - 318. [Abstract] [Full Text] [PDF] |
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M. V. Bautista, Y. Chen, V. S. Ivanova, M. K. Rahimi, A. M. Watson, and M. C. Rose IL-8 Regulates Mucin Gene Expression at the Posttranscriptional Level in Lung Epithelial Cells J. Immunol., August 1, 2009; 183(3): 2159 - 2166. [Abstract] [Full Text] [PDF] |
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J C Lay, N E Alexis, K L Zeman, D B Peden, and W D Bennett In vivo uptake of inhaled particles by airway phagocytes is enhanced in patients with mild asthma compared with normal volunteers Thorax, April 1, 2009; 64(4): 313 - 320. [Abstract] [Full Text] [PDF] |
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S. M. Casalino-Matsuda, M. E. Monzon, A. J. Day, and R. M. Forteza Hyaluronan Fragments/CD44 Mediate Oxidative Stress-Induced MUC5B Up-Regulation in Airway Epithelium Am. J. Respir. Cell Mol. Biol., March 1, 2009; 40(3): 277 - 285. [Abstract] [Full Text] [PDF] |
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H. Tadaki, H. Arakawa, T. Mizuno, T. Suzuki, K. Takeyama, H. Mochizuki, K. Tokuyama, S. Yokota, and A. Morikawa Double-Stranded RNA and TGF-{alpha} Promote MUC5AC Induction in Respiratory Cells J. Immunol., January 1, 2009; 182(1): 293 - 300. [Abstract] [Full Text] [PDF] |
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P-R. Burgel and J. A. Nadel Epidermal growth factor receptor-mediated innate immune responses and their roles in airway diseases Eur. Respir. J., October 1, 2008; 32(4): 1068 - 1081. [Abstract] [Full Text] [PDF] |
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R. G. Crystal, S. H. Randell, J. F. Engelhardt, J. Voynow, and M. E. Sunday Airway Epithelial Cells: Current Concepts and Challenges Proceedings of the ATS, September 15, 2008; 5(7): 772 - 777. [Abstract] [Full Text] [PDF] |
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J-Q. He, A. J. Sandford, I-M. Wang, S. Stepaniants, D. A. Knight, A. Kicic, S. M. Stick, and P. D. Pare Selection of housekeeping genes for real-time PCR in atopic human bronchial epithelial cells Eur. Respir. J., September 1, 2008; 32(3): 755 - 762. [Abstract] [Full Text] [PDF] |
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Y. Nakagami, S. Favoreto Jr, G. Zhen, S.-W. Park, L. T. Nguyenvu, D. A. Kuperman, G. M. Dolganov, X. Huang, H. A. Boushey, P. C. Avila, et al. The Epithelial Anion Transporter Pendrin Is Induced by Allergy and Rhinovirus Infection, Regulates Airway Surface Liquid, and Increases Airway Reactivity and Inflammation in an Asthma Model J. Immunol., August 1, 2008; 181(3): 2203 - 2210. [Abstract] [Full Text] [PDF] |
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K. Schwalm, J. F. Stevens, Z. Jiang, M. R. Schuyler, R. Schrader, S. H. Randell, F. H. Y. Green, and Y. Tesfaigzi Expression of the proapoptotic protein Bax is reduced in bronchial mucous cells of asthmatic subjects Am J Physiol Lung Cell Mol Physiol, June 1, 2008; 294(6): L1102 - L1109. [Abstract] [Full Text] [PDF] |
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L. P. Nguyen, O. Omoluabi, S. Parra, J. M. Frieske, C. Clement, Z. Ammar-Aouchiche, S. B. Ho, C. Ehre, M. Kesimer, B. J. Knoll, et al. Chronic Exposure to Beta-Blockers Attenuates Inflammation and Mucin Content in a Murine Asthma Model Am. J. Respir. Cell Mol. Biol., March 1, 2008; 38(3): 256 - 262. [Abstract] [Full Text] [PDF] |
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C. A. Wu, J. J. Peluso, J. D. Shanley, L. Puddington, and R. S. Thrall Murine Cytomegalovirus Influences Foxj1 Expression, Ciliogenesis, and Mucus Plugging in Mice with Allergic Airway Disease Am. J. Pathol., March 1, 2008; 172(3): 714 - 724. [Abstract] [Full Text] [PDF] |
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C. C. Lewis, J. Y. H. Yang, X. Huang, S. K. Banerjee, M. R. Blackburn, P. Baluk, D. M. McDonald, T. S. Blackwell, V. Nagabhushanam, W. Peters, et al. Disease-Specific Gene Expression Profiling in Multiple Models of Lung Disease Am. J. Respir. Crit. Care Med., February 15, 2008; 177(4): 376 - 387. [Abstract] [Full Text] [PDF] |
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J.-A. Park, A. L. Crews, W. R. Lampe, S. Fang, J. Park, and K. B. Adler Protein Kinase C{delta} Regulates Airway Mucin Secretion via Phosphorylation of MARCKS Protein Am. J. Pathol., December 1, 2007; 171(6): 1822 - 1830. [Abstract] [Full Text] [PDF] |
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D. Y. C. Wu, R. Wu, Y. Chen, N. Tarasova, and M. M. J. Chang PMA Stimulates MUC5B Gene Expression through an Sp1-Based Mechanism in Airway Epithelial Cells Am. J. Respir. Cell Mol. Biol., November 1, 2007; 37(5): 589 - 597. [Abstract] [Full Text] [PDF] |
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G. Q. Ding, C. Q. Zheng, and S. S. Bagga Up-regulation of the Mucosal Epidermal Growth Factor Receptor Gene in Chronic Rhinosinusitis and Nasal Polyposis Arch Otolaryngol Head Neck Surg, November 1, 2007; 133(11): 1097 - 1103. [Abstract] [Full Text] [PDF] |
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H. W. J. Young, O. W. Williams, D. Chandra, L. K. Bellinghausen, G. Perez, A. Suarez, M. J. Tuvim, M. G. Roy, S. N. Alexander, S. J. Moghaddam, et al. Central Role of Muc5ac Expression in Mucous Metaplasia and Its Regulation by Conserved 5' Elements Am. J. Respir. Cell Mol. Biol., September 1, 2007; 37(3): 273 - 290. [Abstract] [Full Text] [PDF] |
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L. Cohen, X. E, J. Tarsi, T. Ramkumar, T. K. Horiuchi, R. Cochran, S. DeMartino, K. B. Schechtman, I. Hussain, M. J. Holtzman, et al. Epithelial Cell Proliferation Contributes to Airway Remodeling in Severe Asthma Am. J. Respir. Crit. Care Med., July 15, 2007; 176(2): 138 - 145. [Abstract] [Full Text] [PDF] |
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A. L. James and S. Wenzel Clinical relevance of airway remodelling in airway diseases Eur. Respir. J., July 1, 2007; 30(1): 134 - 155. [Abstract] [Full Text] [PDF] |
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P. Dillard, R. A. Wetsel, and S. M. Drouin Complement C3a Regulates Muc5ac Expression by Airway Clara Cells Independently of Th2 Responses Am. J. Respir. Crit. Care Med., June 15, 2007; 175(12): 1250 - 1258. [Abstract] [Full Text] [PDF] |
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Q. Wu, R. J. Martin, J. G. Rino, S. Jeyaseelan, R. Breed, and H. W. Chu A deficient TLR2 signaling promotes airway mucin production in Mycoplasma pneumoniae-infected allergic mice Am J Physiol Lung Cell Mol Physiol, May 1, 2007; 292(5): L1064 - L1072. [Abstract] [Full Text] [PDF] |
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I. Kouznetsova, C. E. Chwieralski, R. Balder, M. Hinz, A. Braun, N. Krug, and W. Hoffmann Induced Trefoil Factor Family 1 Expression by Trans-Differentiating Clara Cells in a Murine Asthma Model Am. J. Respir. Cell Mol. Biol., March 1, 2007; 36(3): 286 - 295. [Abstract] [Full Text] [PDF] |
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G. Zhen, S. W. Park, L. T. Nguyenvu, M. W. Rodriguez, R. Barbeau, A. C. Paquet, and D. J. Erle IL-13 and Epidermal Growth Factor Receptor Have Critical but Distinct Roles in Epithelial Cell Mucin Production Am. J. Respir. Cell Mol. Biol., February 1, 2007; 36(2): 244 - 253. [Abstract] [Full Text] [PDF] |
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P.-R. Burgel, D. Montani, C. Danel, D. J Dusser, and J. A Nadel A morphometric study of mucins and small airway plugging in cystic fibrosis Thorax, February 1, 2007; 62(2): 153 - 161. [Abstract] [Full Text] [PDF] |
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D. M. Hyde, L. A. Miller, E. S. Schelegle, M. V. Fanucchi, L. S. Van Winkle, N. K. Tyler, M. V. Avdalovic, M. J. Evans, R. Kajekar, A. R. Buckpitt, et al. Asthma: a comparison of animal models using stereological methods Eur. Respir. Rev., December 1, 2006; 15(101): 122 - 135. [Abstract] [Full Text] [PDF] |
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D. R. Dorscheid, B. J. Patchell, O. Estrada, B. Marroquin, R. Tse, and S. R. White Effects of corticosteroid-induced apoptosis on airway epithelial wound closure in vitro Am J Physiol Lung Cell Mol Physiol, October 1, 2006; 291(4): L794 - L801. [Abstract] [Full Text] [PDF] |
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O. W. Williams, A. Sharafkhaneh, V. Kim, B. F. Dickey, and C. M. Evans Airway Mucus: From Production to Secretion Am. J. Respir. Cell Mol. Biol., May 1, 2006; 34(5): 527 - 536. [Abstract] [Full Text] [PDF] |
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S. M. Casalino-Matsuda, M. E. Monzon, and R. M. Forteza Epidermal Growth Factor Receptor Activation by Epidermal Growth Factor Mediates Oxidant-Induced Goblet Cell Metaplasia in Human Airway Epithelium Am. J. Respir. Cell Mol. Biol., May 1, 2006; 34(5): 581 - 591. [Abstract] [Full Text] [PDF] |
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Y. Tesfaigzi Roles of Apoptosis in Airway Epithelia Am. J. Respir. Cell Mol. Biol., May 1, 2006; 34(5): 537 - 547. [Abstract] [Full Text] [PDF] |
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Y. Chen, T. J. Nickola, N. L. DiFronzo, A. M. Colberg-Poley, and M. C. Rose Dexamethasone-Mediated Repression of MUC5AC Gene Expression in Human Lung Epithelial Cells Am. J. Respir. Cell Mol. Biol., March 1, 2006; 34(3): 338 - 347. [Abstract] [Full Text] [PDF] |
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C. Boxall, S. T. Holgate, and D. E. Davies The contribution of transforming growth factor-{beta} and epidermal growth factor signalling to airway remodelling in chronic asthma Eur. Respir. J., January 1, 2006; 27(1): 208 - 229. [Abstract] [Full Text] [PDF] |
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M. C. Rose and J. A. Voynow Respiratory Tract Mucin Genes and Mucin Glycoproteins in Health and Disease Physiol Rev, January 1, 2006; 86(1): 245 - 278. [Abstract] [Full Text] [PDF] |
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K. Takeda, N. Miyahara, T. Kodama, C. Taube, A. Balhorn, A. Dakhama, K. Kitamura, A. Hirano, M. Tanimoto, and E. W. Gelfand S-carboxymethylcysteine normalises airway responsiveness in sensitised and challenged mice Eur. Respir. J., October 1, 2005; 26(4): 577 - 585. [Abstract] [Full Text] [PDF] |
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D. A. Kuperman, X. Huang, L. Nguyenvu, C. Holscher, F. Brombacher, and D. J. Erle IL-4 Receptor Signaling in Clara Cells Is Required for Allergen-Induced Mucus Production J. Immunol., September 15, 2005; 175(6): 3746 - 3752. [Abstract] [Full Text] [PDF] |
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H. W. Chu, S. Jeyaseelan, J. G. Rino, D. R. Voelker, R. B. Wexler, K. Campbell, R. J. Harbeck, and R. J. Martin TLR2 Signaling Is Critical for Mycoplasma pneumoniae-Induced Airway Mucin Expression J. Immunol., May 1, 2005; 174(9): 5713 - 5719. [Abstract] [Full Text] [PDF] |
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S. Phipps, F. Benyahia, T.-T. Ou, J. Barkans, D. S. Robinson, and A. B. Kay Acute Allergen-Induced Airway Remodeling in Atopic Asthma Am. J. Respir. Cell Mol. Biol., December 1, 2004; 31(6): 626 - 632. [Abstract] [Full Text] [PDF] |
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J. A. Voynow, B. M. Fischer, D. E. Malarkey, L. H. Burch, T. Wong, M. Longphre, S. B. Ho, and W. M. Foster Neutrophil elastase induces mucus cell metaplasia in mouse lung Am J Physiol Lung Cell Mol Physiol, December 1, 2004; 287(6): L1293 - L1302. [Abstract] [Full Text] [PDF] |
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C. J. Danek, C. M. Lombard, D. L. Dungworth, P. G. Cox, J. D. Miller, M. J. Biggs, T. M. Keast, B. E. Loomas, W. J. Wizeman, J. C. Hogg, et al. Reduction in airway hyperresponsiveness to methacholine by the application of RF energy in dogs J Appl Physiol, November 1, 2004; 97(5): 1946 - 1953. [Abstract] [Full Text] [PDF] |
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H. Yoshisue, S. M. Puddicombe, S. J. Wilson, H. M. Haitchi, R. M. Powell, D. I. Wilson, A. Pandit, A. E. Berger, D. E. Davies, S. T. Holgate, et al. Characterization of Ciliated Bronchial Epithelium 1, a Ciliated Cell-Associated Gene Induced During Mucociliary Differentiation Am. J. Respir. Cell Mol. Biol., November 1, 2004; 31(5): 491 - 500. [Abstract] [Full Text] [PDF] |
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P-R Burgel and J A Nadel Roles of epidermal growth factor receptor activation in epithelial cell repair and mucin production in airway epithelium Thorax, November 1, 2004; 59(11): 992 - 996. [Abstract] [Full Text] [PDF] |
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P-R. Burgel, L.O. Cardell, I.F. Ueki, and J.A. Nadel Intranasal steroids decrease eosinophils but not mucin expression in nasal polyps Eur. Respir. J., October 1, 2004; 24(4): 594 - 600. [Abstract] [Full Text] [PDF] |
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H. W. Chu, S. Balzar, G. J. Seedorf, J. Y. Westcott, J. B. Trudeau, P. Silkoff, and S. E. Wenzel Transforming Growth Factor-{beta}2 Induces Bronchial Epithelial Mucin Expression in Asthma Am. J. Pathol., October 1, 2004; 165(4): 1097 - 1106. [Abstract] [Full Text] [PDF] |
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T. Gray, P. Nettesheim, C. Loftin, J.-S. Koo, J. Bonner, S. Peddada, and R. Langenbach Interleukin-1{beta}-Induced Mucin Production in Human Airway Epithelium Is Mediated by Cyclooxygenase-2, Prostaglandin E2 Receptors, and Cyclic AMP-Protein Kinase A Signaling Mol. Pharmacol., August 1, 2004; 66(2): 337 - 346. [Abstract] [Full Text] [PDF] |
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K. Hashimoto, B. S. Graham, S. B. Ho, K. B. Adler, R. D. Collins, S. J. Olson, W. Zhou, T. Suzutani, P. W. Jones, K. Goleniewska, et al. Respiratory Syncytial Virus in Allergic Lung Inflammation Increases Muc5ac and Gob-5 Am. J. Respir. Crit. Care Med., August 1, 2004; 170(3): 306 - 312. [Abstract] [Full Text] [PDF] |
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I. Hussain, V. V. Jain, P. O'Shaughnessy, T. R. Businga, and J. Kline Effect of Nitrogen Dioxide Exposure on Allergic Asthma in a Murine Model Chest, July 1, 2004; 126(1): 198 - 204. [Abstract] [Full Text] [PDF] |
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D. H. Kim, H.-S. Chu, J. Y. Lee, S. J. Hwang, S. H. Lee, and H.-M. Lee Up-regulation of MUC5AC and MUC5B Mucin Genes in Chronic Rhinosinusitis Arch Otolaryngol Head Neck Surg, June 1, 2004; 130(6): 747 - 752. [Abstract] [Full Text] [PDF] |
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M. Chokki, S. Yamamura, H. Eguchi, T. Masegi, H. Horiuchi, H. Tanabe, T. Kamimura, and S. Yasuoka Human Airway Trypsin-Like Protease Increases Mucin Gene Expression in Airway Epithelial Cells Am. J. Respir. Cell Mol. Biol., April 1, 2004; 30(4): 470 - 478. [Abstract] [Full Text] [PDF] |
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Y. Tesfaigzi, J. F. Harris, J. A. Hotchkiss, and J. R. Harkema DNA synthesis and Bcl-2 expression during development of mucous cell metaplasia in airway epithelium of rats exposed to LPS Am J Physiol Lung Cell Mol Physiol, February 1, 2004; 286(2): L268 - L274. [Abstract] [Full Text] [PDF] |
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T. Gray, R. Coakley, A. Hirsh, D. Thornton, S. Kirkham, J.-S. Koo, L. Burch, R. Boucher, and P. Nettesheim Regulation of MUC5AC mucin secretion and airway surface liquid metabolism by IL-1{beta} in human bronchial epithelia Am J Physiol Lung Cell Mol Physiol, February 1, 2004; 286(2): L320 - L330. [Abstract] [Full Text] [PDF] |
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Y. Kaneko, K. Yanagihara, M. Seki, M. Kuroki, Y. Miyazaki, Y. Hirakata, H. Mukae, K. Tomono, J.-i. Kadota, and S. Kohno Clarithromycin inhibits overproduction of muc5ac core protein in murine model of diffuse panbronchiolitis Am J Physiol Lung Cell Mol Physiol, October 1, 2003; 285(4): L847 - L853. [Abstract] [Full Text] [PDF] |
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P. Jeffery, S. Holgate, and S. Wenzel Methods for the Assessment of Endobronchial Biopsies in Clinical Research: Application to Studies of Pathogenesis and the Effects of Treatment Am. J. Respir. Crit. Care Med., September 15, 2003; 168(6): S1 - 17. [Full Text] [PDF] |
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B. E. McParland, P. T. Macklem, and P. D. Pare Airway wall remodeling: friend or foe? J Appl Physiol, July 1, 2003; 95(1): 426 - 434. [Abstract] [Full Text] [PDF] |
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J. R. Reader, D. M. Hyde, E. S. Schelegle, M. C. Aldrich, A. M. Stoddard, M. P. McLane, R. C. Levitt, and J. S. Tepper Interleukin-9 Induces Mucous Cell Metaplasia Independent of Inflammation Am. J. Respir. Cell Mol. Biol., June 1, 2003; 28(6): 664 - 672. [Abstract] [Full Text] [PDF] |
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J. R. Reader, J. S. Tepper, E. S. Schelegle, M. C. Aldrich, L. F. Putney, J. W. Pfeiffer, and D. M. Hyde Pathogenesis of Mucous Cell Metaplasia in a Murine Asthma Model Am. J. Pathol., June 1, 2003; 162(6): 2069 - 2078. [Abstract] [Full Text] [PDF] |
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L. Wang, B. E. McParland, and P. D. Pare The Functional Consequences of Structural Changes in the Airways: Implications for Airway Hyperresponsiveness in Asthma Chest, March 1, 2003; 123 (2009): 356S - 362S. [Full Text] [PDF] |
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J. V. Fahy Goblet Cell and Mucin Gene Abnormalities in Asthma Chest, December 1, 2002; 122 (2009): 320S - 326S. [Abstract] [Full Text] [PDF] |
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Y. Tesfaigzi, M. J. Fischer, M. Daheshia, F. H. Y. Green, G. T. De Sanctis, and J. A. Wilder Bax is Crucial for IFN-{gamma}-Induced Resolution of Allergen- Induced Mucus Cell Metaplasia J. Immunol., November 15, 2002; 169(10): 5919 - 5925. [Abstract] [Full Text] [PDF] |
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N. J. Vanacker, E. Palmans, R. A. Pauwels, and J. C. Kips Effect of Combining Salmeterol and Fluticasone on the Progression of Airway Remodeling Am. J. Respir. Crit. Care Med., October 15, 2002; 166(8): 1128 - 1134. [Abstract] [Full Text] [PDF] |
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M. J. TOBIN Asthma, Airway Biology, and Nasal Disorders in AJRCCM 2001 Am. J. Respir. Crit. Care Med., March 1, 2002; 165(5): 598 - 618. [Full Text] [PDF] |
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J. V. FAHY Remodeling of the Airway Epithelium in Asthma Am. J. Respir. Crit. Care Med., November 15, 2001; 164(10): S46 - 51. [Abstract] [Full Text] [PDF] |
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P.-R. Burgel, S. C. Lazarus, D. C.-W. Tam, I. F. Ueki, K. Atabai, M. Birch, and J. A. Nadel Human Eosinophils Induce Mucin Production in Airway Epithelial Cells Via Epidermal Growth Factor Receptor Activation J. Immunol., November 15, 2001; 167(10): 5948 - 5954. [Abstract] [Full Text] [PDF] |
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M. C. Rose, T. J. Nickola, and J. A. Voynow Airway Mucus Obstruction: Mucin Glycoproteins, MUC Gene Regulation and Goblet Cell Hyperplasia Am. J. Respir. Cell Mol. Biol., November 1, 2001; 25(5): 533 - 537. [Full Text] [PDF] |
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T. SHIMIZU, H. HIRANO, S. SHIMIZU, C. KISHIOKA, Y. SAKAKURA, and Y. MAJIMA Differential Properties of Mucous Glycoproteins in Rat Nasal Epithelium . A Comparison between Allergic Inflammation and Lipopolysaccharide Stimulation Am. J. Respir. Crit. Care Med., September 15, 2001; 164(6): 1077 - 1082. [Abstract] [Full Text] [PDF] |
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G. M. Dolganov, P. G. Woodruff, A. A. Novikov, Y. Zhang, R. E. Ferrando, R. Szubin, and J. V. Fahy A Novel Method of Gene Transcript Profiling in Airway Biopsy Homogenates Reveals Increased Expression of a Na+-K+-Cl- Cotransporter (NKCC1) in Asthmatic Subjects Genome Res., September 1, 2001; 11(9): 1473 - 1483. [Abstract] [Full Text] [PDF] |
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