help button home button
AJRCCM
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by CRINER, G. J.
Right arrow Articles by O'BRIEN, G. M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by CRINER, G. J.
Right arrow Articles by O'BRIEN, G. M.

Am. J. Respir. Crit. Care Med., Volume 160, Number 6, December 1999, 2018-2027

Prospective Randomized Trial Comparing Bilateral Lung Volume Reduction Surgery to Pulmonary Rehabilitation in Severe Chronic Obstructive Pulmonary Disease

GERARD J. CRINER, FRANCIS C. CORDOVA, SATOSHI FURUKAWA, ANN MARIE KUZMA, JOHN M. TRAVALINE, VADIM LEYENSON, and GERARD M. O'BRIEN

Divisions of Pulmonary and Critical Care Medicine, Department of Medicine and Cardiothoracic Surgery, Department of Surgery, Temple University School of Medicine, Philadelphia, Pennsylvania

Several uncontrolled studies report improvement in lung function, gas exchange, and exercise capacity after bilateral lung volume reduction surgery (LVRS). We recruited 200 patients with severe chronic obstructive pulmonary disease (COPD) for a prospective randomized trial of pulmonary rehabilitation versus bilateral LVRS with stapling resection of 20 to 40% of each lung. Pulmonary function tests, gas exchange, 6-min walk distance, and symptom-limited maximal exercise testing were done in all patients at baseline and after 8 wk of rehabilitation. Patients were then randomized to either 3 additional months of rehabilitation or LVRS. Thirty-seven patients met study criteria and were enrolled into the trial. Eighteen patients were in the medical arm; 15 of 18 patients completed 3 mo of additional pulmonary rehabilitation. Thirty-two patients underwent LVRS (19 in the surgical arm, 13 crossover from the medical arm). After 8 wk of pulmonary rehabilitation, pulmonary function tests remained unchanged compared with baseline data. However, there was a trend toward a higher 6-min walk distance (285 ± 96 versus 269 ± 91 m, p = 0.14) and total exercise time on maximal exercise test was significantly longer compared with baseline values (7.4 ± 2.1 versus 5.8 ± 1.7 min, p < 0.001). In 15 patients who completed 3 mo of additional rehabilitation, there was a trend to a higher maximal oxygen consumption (V O2max) (13.3 ± 3.0 versus 12.6 ± 3.3, p < 0.08). In contrast, at 3 mo post-LVRS, FVC (2.79 ± 0.59 versus 2.36 ± 0.55 L, p < 0.001) and FEV1 (0.85 ± 0.3 versus 0.65 ± 0.16 L, p < 0.005) increased whereas TLC (6.53 ± 1.3 versus 7.65 ± 2.1 L, p < 0.001) and residual volume (RV) (3.7 ± 1.2 versus 4.9 ± 1.1 L, p < 0.001) decreased when compared with 8 wk postrehabilitation data. In addition, PaCO2 decreased significantly 3 mo post-LVRS compared with 8 wk postrehabilitation. Six-minute walk distance (6MWD), total exercise time, and V O2max were higher after LVRS but did not reach statistical significance. However, when 13 patients who crossed over from the medical to the surgical arm were included in the analysis, the increases in 6MWD (337 ± 99 versus 282 ± 100 m, p < 0.001) and V O2max (13.8 ± 4 versus 12.0 ± 3 ml/kg/min, p < 0.01) 3 mo post-LVRS were highly significant when compared with postrehabilitation data. The Sickness Impact Profile (SIP), a generalized measure of quality of life (QOL), was significantly improved after 8 wk of rehabilitation and was maintained after 3 mo of additional rehabilitation. A further improvement in QOL was observed 3 mo after LVRS compared with the initial improvement gained after 8 wk of rehabilitation. There were 3 (9.4%) postoperative deaths, and one patient died before surgery (2.7%). We conclude that bilateral LVRS, in addition to pulmonary rehabilitation, improves static lung function, gas exchange, and QOL compared with pulmonary rehabilitation alone. Further studies need to evaluate the risks, benefits, and durability of LVRS over time. Criner GJ, Cordova FC, Furukawa S, Kuzma AM, Travaline JM, Leyenson V, O'Brien GM. Prospective randomized trial comparing bilateral lung volume reduction surgery to pulmonary rehabilitation in severe chronic obstructive pulmonary disease.




This article has been cited by other articles:


Home page
 ChestHome page
G. J. Criner, P. Belt, A. L. Sternberg, Z. Mosenifar, B. J. Make, J. P. Utz, F. Sciurba, and for the National Emphysema Treatment Trial Researc
Effects of Lung Volume Reduction Surgery on Gas Exchange and Breathing Pattern During Maximum Exercise
Chest, May 1, 2009; 135(5): 1268 - 1279.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
W. Weder, M. Tutic, D. Lardinois, W. Jungraithmayr, S. Hillinger, E. W. Russi, and K. E. Bloch
Persistent Benefit From Lung Volume Reduction Surgery in Patients With Homogeneous Emphysema
Ann. Thorac. Surg., January 1, 2009; 87(1): 229 - 237.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
M. L. Snyder, C. H. Goss, B. Neradilek, N. L. Polissar, Z. Mosenifar, R. A. Wise, A. P. Fishman, J. O. Benditt, and for the National Emphysema Treatment Trial Researc
Changes in Arterial Oxygenation and Self-Reported Oxygen Use after Lung Volume Reduction Surgery
Am. J. Respir. Crit. Care Med., August 15, 2008; 178(4): 339 - 345.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
B. R. Celli
Update on the Management of COPD
Chest, June 1, 2008; 133(6): 1451 - 1462.
[Abstract] [Full Text] [PDF]

Home page
 Proc Am Thorac SocHome page
E. P. Ingenito, D. E. Wood, and J. P. Utz
Bronchoscopic Lung Volume Reduction in Severe Emphysema
Proceedings of the ATS, May 1, 2008; 5(4): 454 - 460.
[Abstract] [Full Text] [PDF]

Home page
 JNMHome page
J. J. Mathews, A. H. Maurer, R. M. Steiner, N. Marchetti, G. Criner, J. P. Gaughan, and H. O. Coxson
New 133Xe Gas Trapping Index for Quantifying Severe Emphysema Before Partial Lung Volume Reduction
J. Nucl. Med., May 1, 2008; 49(5): 771 - 775.
[Abstract] [Full Text] [PDF]

Home page
 Eur Respir JHome page
O. Georgiadou, I. Vogiatzis, G. Stratakos, A. Koutsoukou, S. Golemati, A. Aliverti, C. Roussos, and S. Zakynthinos
Effects of rehabilitation on chest wall volume regulation during exercise in COPD patients
Eur. Respir. J., February 1, 2007; 29(2): 284 - 291.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
D. E. Wood, R. J. McKenna Jr, R. D. Yusen, D. H. Sterman, D. E. Ost, S. C. Springmeyer, H. X. Gonzalez, M. S. Mulligan, T. Gildea, W. V. Houck, et al.
A multicenter trial of an intrabronchial valve for treatment of severe emphysema
J. Thorac. Cardiovasc. Surg., January 1, 2007; 133(1): 65 - 73.
[Abstract] [Full Text] [PDF]

Home page
 ERRHome page
M. I. Polkey
Surgical procedures in emphysema: any impact on dynamic hyperinflation?
Eur. Respir. Rev., December 1, 2006; 15(100): 96 - 99.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
T. C. Mineo, E. Pompeo, D. Mineo, V. Ambrogi, D. Ciarapica, and A. Polito
Resting energy expenditure and metabolic changes after lung volume reduction surgery for emphysema.
Ann. Thorac. Surg., October 1, 2006; 82(4): 1205 - 1211.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
K. S. Naunheim, D. E. Wood, Z. Mohsenifar, A. L. Sternberg, G. J. Criner, M. M. DeCamp, C. C. Deschamps, F. J. Martinez, F. C. Sciurba, J. Tonascia, et al.
Long-Term Follow-Up of Patients Receiving Lung-Volume-Reduction Surgery Versus Medical Therapy for Severe Emphysema by the National Emphysema Treatment Trial Research Group
Ann. Thorac. Surg., August 1, 2006; 82(2): 431 - 443.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
M. Tutic, D. Lardinois, S. Imfeld, S. Korom, A. Boehler, R. Speich, K. E. Bloch, E. W. Russi, and W. Weder
Lung-volume reduction surgery as an alternative or bridging procedure to lung transplantation.
Ann. Thorac. Surg., July 1, 2006; 82(1): 208 - 213.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
L. Nici, C. Donner, E. Wouters, R. Zuwallack, N. Ambrosino, J. Bourbeau, M. Carone, B. Celli, M. Engelen, B. Fahy, et al.
American thoracic society/european respiratory society statement on pulmonary rehabilitation.
Am. J. Respir. Crit. Care Med., June 15, 2006; 173(12): 1390 - 1413.
[Full Text] [PDF]

Home page
 ThoraxHome page
T Higuchi, A Reed, T Oto, L Holsworth, S Ellis, M J Bailey, T J Williams, and G I Snell
Relation of interlobar collaterals to radiological heterogeneity in severe emphysema
Thorax, May 1, 2006; 61(5): 409 - 413.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
J. D. Miller, R. A. Malthaner, C. H. Goldsmith, R. Goeree, D. Higgins, P. G. Cox, L. Tan, J. D. Road, and Canadian Lung Volume Reduction Surgery Study
A Randomized Clinical Trial of Lung Volume Reduction Surgery Versus Best Medical Care for Patients With Advanced Emphysema: A Two-Year Study From Canada
Ann. Thorac. Surg., January 1, 2006; 81(1): 314 - 321.
[Abstract] [Full Text] [PDF]

Home page
 Proc Am Thorac SocHome page
B. R. Celli
Chronic Obstructive Pulmonary Disease: From Unjustified Nihilism to Evidence-based Optimism.
Proceedings of the ATS, January 1, 2006; 3(1): 58 - 65.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
S. L. Krachman, W. Chatila, U. J. Martin, T. Nugent, J. Crocetti, J. Gaughan, G. J. Criner, and for the National Emphysema Treatment Trial Researc
Effects of Lung Volume Reduction Surgery on Sleep Quality and Nocturnal Gas Exchange in Patients With Severe Emphysema
Chest, November 1, 2005; 128(5): 3221 - 3228.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
G. Hillerdal, C.-G. Lofdahl, K. Strom, B.-E. Skoogh, L. Jorfeldt, F. Nilsson, D. Forslund-Stiby, J. Ranstam, E. Gyllstedt, and of the Swedish VOLREM Group
Comparison of Lung Volume Reduction Surgery and Physical Training on Health Status and Physiologic Outcomes: A Randomized Controlled Clinical Trial
Chest, November 1, 2005; 128(5): 3489 - 3499.
[Abstract] [Full Text] [PDF]

Home page
 Eur Respir JHome page
P. J. Barnes and R. A. Stockley
COPD: current therapeutic interventions and future approaches
Eur. Respir. J., June 1, 2005; 25(6): 1084 - 1106.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
T. C. Mineo, V. Ambrogi, D. Mineo, A. Fabbri, E. Fabbrini, and R. Massoud
Bone Mineral Density Improvement After Lung Volume Reduction Surgery for Severe Emphysema
Chest, June 1, 2005; 127(6): 1960 - 1966.
[Abstract] [Full Text] [PDF]

Home page
 Chronic Respiratory DiseaseHome page
Z J McKeoughl, J A Alison, M S Bayfield, and P T.P Bye
Supported and unsupported arm exercise capacity following lung volume reduction surgery: a pilot study
Chronic Respiratory Disease, April 1, 2005; 2(2): 59 - 65.
[Abstract] [PDF]

Home page
 ChestHome page
J. D. Miller, R. L. Berger, R. A. Malthaner, B. R. Celli, C. H. Goldsmith, E. P. Ingenito, D. Higgins, P. Bagley, G. Cox, and C. D. Wright
Lung Volume Reduction Surgery vs Medical Treatment: For Patients With Advanced Emphysema
Chest, April 1, 2005; 127(4): 1166 - 1177.
[Abstract] [Full Text] [PDF]

Home page
 ThoraxHome page
A Sharafkhaneh, S Goodnight-White, T M Officer, J R Rodarte, and A M Boriek
Altered thoracic gas compression contributes to improvement in spirometry with lung volume reduction surgery
Thorax, April 1, 2005; 60(4): 288 - 292.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
V. Kim, G. J. Criner, H. Y. Abdallah, J. P. Gaughan, S. Furukawa, and C. C. Solomides
Small Airway Morphometry and Improvement in Pulmonary Function after Lung Volume Reduction Surgery
Am. J. Respir. Crit. Care Med., January 1, 2005; 171(1): 40 - 47.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
M. Tutic, K. E. Bloch, D. Lardinois, T. Brack, E. W. Russi, and W. Weder
Long-term results after lung volume reduction surgery in patients with {alpha}1-antitrypsin deficiency
J. Thorac. Cardiovasc. Surg., September 1, 2004; 128(3): 408 - 413.
[Abstract] [Full Text] [PDF]

Home page
 Eur Respir JHome page
N. Ambrosino and S. Strambi
New strategies to improve exercise tolerance in chronic obstructive pulmonary disease
Eur. Respir. J., August 1, 2004; 24(2): 313 - 322.
[Abstract] [Full Text] [PDF]

Home page
 Eur Respir JHome page
T.E. Dolmage, T.K. Waddell, F. Maltais, G.H. Guyatt, T.R.J. Todd, S. Keshavjee, S. van Rooy, B. Krip, P. LeBlanc, and R.S. Goldstein
The influence of lung volume reduction surgery on exercise in patients with COPD
Eur. Respir. J., February 1, 2004; 23(2): 269 - 274.
[Abstract] [Full Text] [PDF]

Home page
 Eur Respir JHome page
T.C. Mineo, V. Ambrogi, E. Pompeo, S. Elia, D. Mineo, P. Bollero, and I. Nofroni
Impact of lung volume reduction surgery versus rehabilitation on quality of life
Eur. Respir. J., February 1, 2004; 23(2): 275 - 280.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
S. N. Mink, X. Gonzalez, K. Duke, E. Bautista, and L. Tan
Lung Volume Reduction Surgery in Canine Model of Predominantly Upper Lobe Emphysema: Advantages of New Surgical System
Chest, February 1, 2004; 125(2): 633 - 643.
[Abstract] [Full Text] [PDF]

Home page
 Chronic Respiratory DiseaseHome page
D A Lomas
Lung volume reduction surgery: where are we now?
Chronic Respiratory Disease, January 1, 2004; 1(1): 2 - 4.
[PDF]

Home page
 JAMAHome page
B. R. Celli
A 62-Year-Old Woman With Chronic Obstructive Pulmonary Disease
JAMA, November 26, 2003; 290(20): 2721 - 2729.
[Full Text] [PDF]

Home page
 Eur Respir JHome page
M. Decramer
Treatment of chronic respiratory failure: lung volume reduction surgery versus rehabilitation
Eur. Respir. J., November 16, 2003; 22(47_suppl): 47s - 56s.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
K. Jorgensen, E. Houltz, U. Westfelt, F. Nilsson, H. Schersten, and S.-E. Ricksten
Effects of Lung Volume Reduction Surgery on Left Ventricular Diastolic Filling and Dimensions in Patients With Severe Emphysema
Chest, November 1, 2003; 124(5): 1863 - 1870.
[Abstract] [Full Text] [PDF]

Home page
 Eur Respir JHome page
E.W. Russi, K.E. Bloch, and W. Weder
Lung volume reduction surgery: what can we learn from the National Emphysema Treatment Trial?
Eur. Respir. J., October 1, 2003; 22(4): 571 - 573.
[Full Text] [PDF]

Home page
 ChestHome page
P. E. Munro, M. J. Bailey, J. A. Smith, and G. I. Snell
Lung Volume Reduction Surgery in Australia and New Zealand: Six Years On: Registry Report
Chest, October 1, 2003; 124(4): 1443 - 1450.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
G. I. Snell, L. Holsworth, Z. L. Borrill, K. R. Thomson, V. Kalff, J. A. Smith, and T. J. Williams
The Potential for Bronchoscopic Lung Volume Reduction Using Bronchial Prostheses: A Pilot Study
Chest, September 1, 2003; 124(3): 1073 - 1080.
[Abstract] [Full Text] [PDF]

Home page
 ThoraxHome page
P M A Calverley
Closing the NETT on lung volume reduction surgery
Thorax, August 1, 2003; 58(8): 651 - 653.
[Full Text]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
Y.-C. Lee, Y.-L. Chang, C.-W. Chen, N.-C. Chien, and P.-M. Huang
Use of autologous pleural flap buttress in thoracoscopic lung volume reduction surgery
J. Thorac. Cardiovasc. Surg., July 1, 2003; 126(1): 298 - 299.
[Full Text] [PDF]

Home page
 ThoraxHome page
B F Meyers and G A Patterson
Chronic obstructive pulmonary disease * 10: Bullectomy, lung volume reduction surgery, and transplantation for patients with chronic obstructive pulmonary disease
Thorax, July 1, 2003; 58(7): 634 - 638.
[Abstract] [Full Text] [PDF]

Home page
 Eur. J. Cardiothorac. Surg.Home page
S. Provencher and J. Deslauriers
Late complication of bovine pericardium patches used for lung volume reduction surgery
Eur. J. Cardiothorac. Surg., June 1, 2003; 23(6): 1059 - 1061.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
S. Appleton, R. Adams, S. Porter, M. Peacock, and R. Ruffin
Sustained Improvements in Dyspnea and Pulmonary Function 3 to 5 Years After Lung Volume Reduction Surgery
Chest, June 1, 2003; 123(6): 1838 - 1846.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
F. Sciurba, G. J. Criner, S. M. Lee, Z. Mohsenifar, D. Shade, W. Slivka, and R. A. Wise
Six-Minute Walk Distance in Chronic Obstructive Pulmonary Disease: Reproducibility and Effect of Walking Course Layout and Length
Am. J. Respir. Crit. Care Med., June 1, 2003; 167(11): 1522 - 1527.
[Abstract] [Full Text] [PDF]

Home page
 NEJMHome page
National Emphysema Treatment Trial Research Group
A Randomized Trial Comparing Lung-Volume-Reduction Surgery with Medical Therapy for Severe Emphysema
N. Engl. J. Med., May 22, 2003; 348(21): 2059 - 2073.
[Abstract] [Full Text] [PDF]

Home page
 ThoraxHome page
R S Goldstein, T R J Todd, G Guyatt, S Keshavjee, T E Dolmage, S van Rooy, B Krip, F Maltais, P LeBlanc, S Pakhale, et al.
Influence of lung volume reduction surgery (LVRS) on health related quality of life in patients with chronic obstructive pulmonary disease
Thorax, May 1, 2003; 58(5): 405 - 410.
[Abstract] [Full Text] [PDF]

Home page
 ThoraxHome page
W MacNee and P M A Calverley
Chronic obstructive pulmonary disease * 7: Management of COPD
Thorax, March 1, 2003; 58(3): 261 - 265.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
E. P. Ingenito, S. H. Loring, M. L. Moy, S. J. Mentzer, S. J. Swanson, and J. J. Reilly
Physiological characterization of variability in response to lung volume reduction surgery
J Appl Physiol, January 1, 2003; 94(1): 20 - 30.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
T. C. Mineo, V. Ambrogi, E. Pompeo, P. Bollero, D. Mineo, and I. Nofroni
Body weight and nutritional changes after reduction pneumoplasty for severe emphysema: A randomized study
J. Thorac. Cardiovasc. Surg., October 1, 2002; 124(4): 660 - 667.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
ATS Statement: Guidelines for the Six-Minute Walk Test
Am. J. Respir. Crit. Care Med., July 1, 2002; 166(1): 111 - 117.
[Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
K. E. Bloch, C. L. Georgescu, E. W. Russi, and W. Weder
Gain and subsequent loss of lung function after lung volume reduction surgery in cases of severe emphysema with different morphologic patterns
J. Thorac. Cardiovasc. Surg., May 1, 2002; 123(5): 845 - 854.
[Abstract] [Full Text] [PDF]

Home page
 Eur. J. Cardiothorac. Surg.Home page
E. Pompeo and T. C. Mineo
Long-term outcome of staged versus one-stage bilateral thoracoscopic reduction pneumoplasty
Eur. J. Cardiothorac. Surg., April 1, 2002; 21(4): 627 - 633.
[Abstract] [Full Text] [PDF]

Home page
 Eur Respir JHome page
E. Marchand, P. De Leyn, G. Gayan-Ramirez, F. Palecek, E. Verbeken, and M. Decramer
Effects of lung volume reduction surgery in hamsters with elastase-induced emphysema
Eur. Respir. J., March 1, 2002; 19(3): 422 - 428.
[Abstract] [Full Text] [PDF]

Home page
 Eur Respir JHome page
J. Hamacher, S. Buchi, C.L. Georgescu, U. Stammberger, R. Thurnheer, K.E. Bloch, W. Weder, and E.W. Russi
Improved quality of life after lung volume reduction surgery
Eur. Respir. J., January 1, 2002; 19(1): 54 - 60.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
M. Brenner, X. Gonzalez, B. Jones, R. Ha, K. Osann, R. McKenna, and J. Milliken
Effects of a Novel Implantable Elastomer Device for Lung Volume Reduction Surgery in a Rabbit Model of Elastase-Induced Emphysema
Chest, January 1, 2002; 121(1): 201 - 209.
[Abstract] [Full Text] [PDF]

Home page
 ThoraxHome page
T P Toma, P Goldstraw, and D M Geddes
Lung volume reduction surgery
Thorax, January 1, 2002; 57(1): 5 - 5.
[Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
Y. NAKANO, H. O. COXSON, S. BOSAN, R. M. ROGERS, F. C. SCIURBA, R. J. KEENAN, K. R. WALLEY, P. D. PARE, and J. C. HOGG
Core to Rind Distribution of Severe Emphysema Predicts Outcome of Lung Volume Reduction Surgery
Am. J. Respir. Crit. Care Med., December 15, 2001; 164(12): 2195 - 2199.
[Abstract] [Full Text] [PDF]

Home page
 BMJHome page
H. A M Kerstjens, H. J Groen, and W. van der Bij
Recent advances: Respiratory medicine
BMJ, December 8, 2001; 323(7325): 1349 - 1353.
[Full Text] [PDF]

Home page
 ChestHome page
R. M. Kotloff, J. Hansen-Flaschen, D. A. Lipson, G. Tino, S. M. Arcasoy, A. Alavi, and L. R. Kaiser
Apical Perfusion Fraction as a Predictor of Short-term Functional Outcome Following Bilateral Lung Volume Reduction Surgery
Chest, November 1, 2001; 120(5): 1609 - 1615.
[Abstract] [Full Text] [PDF]

Home page
 ThoraxHome page
British Thoracic Society Standards of Care Subcomm
Pulmonary rehabilitation
Thorax, November 1, 2001; 56(11): 827 - 834.
[Full Text] [PDF]

Home page
 NEJMHome page
National Emphysema Treatment Trial Research Group
Patients at High Risk of Death after Lung-Volume-Reduction Surgery
N. Engl. J. Med., October 11, 2001; 345(15): 1075 - 1083.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
G. R. Stirling, W. J. Babidge, M. J. Peacock, J. A. Smith, K. S. Matar, G. I. Snell, D. J. Colville, and G. J. Maddern
Lung volume reduction surgery in emphysema: a systematic review
Ann. Thorac. Surg., August 1, 2001; 72(2): 641 - 648.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
A. F. GELB, R. J. McKENNA Jr., M. BRENNER, J. D. EPSTEIN, and N. ZAMEL
Lung Function 5 yr after Lung Volume Reduction Surgery for Emphysema
Am. J. Respir. Crit. Care Med., June 1, 2001; 163(7): 1562 - 1566.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
A. F. Gelb, R. J. McKenna Jr, and M. Brenner
Expanding Knowledge of Lung Volume Reduction
Chest, May 1, 2001; 119(5): 1300 - 1303.
[Full Text] [PDF]

Home page
 ChestHome page
K. R. Flaherty, E. A. Kazerooni, J. L. Curtis, M. Iannettoni, L. Lange, M. A. Schork, and F. J. Martinez
Short-term and Long-term Outcomes After Bilateral Lung Volume Reduction Surgery : Prediction by Quantitative CT
Chest, May 1, 2001; 119(5): 1337 - 1346.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
W. CHATILA, S. FURUKAWA, and G. J. CRINER
Acute Respiratory Failure after Lung Volume Reduction Surgery
Am. J. Respir. Crit. Care Med., October 1, 2000; 162(4): 1292 - 1296.
[Abstract] [Full Text] [PDF]

Home page
 Ann. Thorac. Surg.Home page
E. Pompeo, M. Marino, I. Nofroni, G. Matteucci, and T. C. Mineo
Reduction pneumoplasty versus respiratory rehabilitation in severe emphysema: a randomized study
Ann. Thorac. Surg., September 1, 2000; 70(3): 948 - 953.
[Abstract] [Full Text] [PDF]

Home page
 NEJMHome page
P. J. Barnes
Chronic Obstructive Pulmonary Disease
N. Engl. J. Med., July 27, 2000; 343(4): 269 - 280.
[Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Proc. Am. Thorac. Soc. Am. J. Respir. Cell Mol. Biol.
Copyright © 1999 American Thoracic Society 		  Red Transition