Am. J. Respir. Crit. Care Med., Volume 160, Number 4, October 1999, 1248-1253

Exercise Rehabilitation and Chronic Obstructive Pulmonary Disease Stage

MICHAEL J. BERRY, W. JACK REJESKI, NORMAN E. ADAIR, and DANIEL ZACCARO

Department of Health and Exercise Science, Department of Public Health Science, and Department of Medicine, Wake Forest University, Winston-Salem, North Carolina

To determine the extent to which patients with Stage I COPD experience improvements in physical performance and quality of life as a result of exercise training, and to compare these improvements with those seen in Stage I and II patients, 151 patients with COPD underwent a 12-wk exercise program. Outcomes were measured at baseline and follow-up. Physical performance was evaluated by means of a 6-min walk, treadmill time, an overhead task, and a stair climb. General health-related quality of life was assessed in terms of the domains of Social Function, Health Perceptions, and Life Satisfaction. Disease-specific health-related quality of life was assessed with the Chronic Respiratory Disease Questionnaire (CRQ). Six-minute walk distance increased significantly in Stage I (200.5 ft [95% CI: 165.4, 235.7]), Stage II (238.3 ft [143.3, 333.3]), and Stage III (112.1 ft [34.6, 189.6]) participants. Treadmill time increased significantly in Stage I (0.42 min [0.20, 0.64]) and Stage II (0.64 min [0.14, 1.4]) participants. Time to complete the overhead task decreased significantly in Stage I (0.91 s [1.72, 0.11]) and Stage II (1.39 s [2.66, 0.13]) participants. None of the measures of general health-related quality of life improved in any of the three groups. Participants in Stages I, II, and III all experienced improvements in the CRQ domains of dyspnea (0.72 [0.53, 0.91], 0.47 [0.02, 0.91], and 0.46 [0.05, 0.87], respectively) and fatigue (0.49 [0.33, 0.66], 0.54 [0.20, 0.87], and 0.55 [0.05, 1.05], respectively). These results suggest that all patients with COPD will benefit from exercise rehabilitation. Berry MJ, Rejeski WJ, Adair NE, Zaccaro D. Exercise rehabilitation and chronic obstructive pulmonary disease stage.

This article has been cited by other articles:

				H. R Gosker, M. P Zeegers, E. F M Wouters, and A. M W J Schols Muscle fibre type shifting in the vastus lateralis of patients with COPD is associated with disease severity: a systematic review and meta-analysis Thorax, November 1, 2007; 62(11): 944 - 949. [Abstract] [Full Text] [PDF]

				R. Porta, M. Vitacca, L. S. Gile, E. Clini, L. Bianchi, E. Zanotti, and N. Ambrosino Supported Arm Training in Patients Recently Weaned From Mechanical Ventilation Chest, October 1, 2005; 128(4): 2511 - 2520. [Abstract] [Full Text] [PDF]

				T. Troosters, R. Casaburi, R. Gosselink, and M. Decramer Pulmonary Rehabilitation in Chronic Obstructive Pulmonary Disease Am. J. Respir. Crit. Care Med., July 1, 2005; 172(1): 19 - 38. [Full Text] [PDF]

				G. Rossi, F. Florini, M. Romagnoli, T. Bellantone, S. Lucic, D. Lugli, and E. Clini Length and Clinical Effectiveness of Pulmonary Rehabilitation in Outpatients With Chronic Airway Obstruction Chest, January 1, 2005; 127(1): 105 - 109. [Abstract] [Full Text] [PDF]

				J. J. Egan The Clinical Practice of Lung Transplantation in North America Chest, April 1, 2004; 125(4): 1183 - 1184. [Full Text] [PDF]

				M. Decramer Treatment of chronic respiratory failure: lung volume reduction surgery versus rehabilitation Eur. Respir. J., November 16, 2003; 22(47_suppl): 47S - 56s. [Abstract] [Full Text] [PDF]

				E. C. Creutzberg, E. F. M. Wouters, R. Mostert, R. J. Pluymers, and A. M. W. J. Schols A Role for Anabolic Steroids in the Rehabilitation of Patients With COPD?: A Double-Blind, Placebo-Controlled, Randomized Trial Chest, November 1, 2003; 124(5): 1733 - 1742. [Abstract] [Full Text] [PDF]

				E. Clini, K. Foglio, L. Bianchi, R. Porta, M. Vitacca, and N. Ambrosino In-Hospital Short-term Training Program for Patients With Chronic Airway Obstruction Chest, November 1, 2001; 120(5): 1500 - 1505. [Abstract] [Full Text] [PDF]

				British Thoracic Society Standards of Care Subcomm Pulmonary rehabilitation Thorax, November 1, 2001; 56(11): 827 - 834. [Full Text] [PDF]

				B. W. J. H. Penninx, S. P. Messier, W. J. Rejeski, J. D. Williamson, M. DiBari, C. Cavazzini, W. B. Applegate, and M. Pahor Physical Exercise and the Prevention of Disability in Activities of Daily Living in Older Persons With Osteoarthritis Arch Intern Med, October 22, 2001; 161(19): 2309 - 2316. [Abstract] [Full Text] [PDF]

				K. Foglio, L. Bianchi, and N. Ambrosino Is It Really Useful To Repeat Outpatient Pulmonary Rehabilitation Programs in Patients With Chronic Airway Obstruction? : A 2-Year Controlled Study Chest, June 1, 2001; 119(6): 1696 - 1704. [Abstract] [Full Text] [PDF]

				R. A. PAUWELS, A. S. BUIST, P. M. A. CALVERLEY, C. R. JENKINS, and S. S. HURD Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease . NHLBI/WHO Global Initiative for Chronic Obstructive Lung Disease (GOLD) Workshop Summary Am. J. Respir. Crit. Care Med., April 1, 2001; 163(5): 1256 - 1276. [Full Text]

				C. G. Foy, W. J. Rejeski, M. J. Berry, D. Zaccaro, and C. M. Woodard Gender Moderates the Effects of Exercise Therapy on Health-Related Quality of Life Among COPD Patients Chest, January 1, 2001; 119(1): 70 - 76. [Abstract] [Full Text] [PDF]

				M. Yoshikawa, T. Yoneda, H. Takenaka, A. Fukuoka, Y. Okamoto, N. Narita, and K. Nezu Distribution of Muscle Mass and Maximal Exercise Performance in Patients With COPD Chest, January 1, 2001; 119(1): 93 - 98. [Abstract] [Full Text] [PDF]