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Am. J. Respir. Crit. Care Med., Volume 160, Number 2, August 1999, 730-731

Bronchoalveolar Lavage Fluid Granulomas in a Case of Severe Sarcoidosis

MARK V. HENDRICKS, JOHN H. CROSBY, and W. BRUCE DAVIS

Section of Pulmonary Diseases, Department of Medicine, and Department of Pathology, Medical College of Georgia, Augusta, Georgia

A case of pulmonary sarcoidosis is presented in which cytologic analysis of bronchoalveolar (BAL) fluid showed intact granulomas. The patient had severe alveolar inflammation and probable endobronchial sarcoidosis. Thus the granulomas in the BAL fluid probably reflect a high burden of alveolar wall granulomas and/or the removal of granulomas from proximal inflamed airways. This is the first reported case of granulomas in BAL fluid in sarcoidosis. Although an unusual finding, the recovery of BAL granulomas is not diagnostic for sarcoidosis and cannot substitute for the demonstration of granulomatous inflammation in lung tissue.






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Proc. Am. Thorac. Soc. Am. J. Respir. Cell Mol. Biol.
Copyright © 1999 American Thoracic Society 		  Tobacco