help button home button
AJRCCM
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by RELLO, J.
Right arrow Articles by VALLÉS, J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by RELLO, J.
Right arrow Articles by VALLÉS, J.

Am. J. Respir. Crit. Care Med., Volume 159, Number 6, June 1999, 1742-1746

Risk Factors for Developing Pneumonia within 48 Hours of Intubation

JORDI RELLO, EMILI DIAZ, MARTA ROQUE, and JORDI VALLÉS

Pulmonary and Critical Care Departments, Hospital de Sabadell, and CEPSS/FPT, Sabadell, Barcelona, Spain

Two hundred fifty intubated patients were followed during the first 48 h after intubation in order to identify potential risk factors for developing pneumonia within this period. Thirty-two developed pneumonia during this time. Univariate analysis established that large volume aspiration, presence of sedation, intubation caused by respiratory/cardiac arrest or decrease in the level of consciousness, emergency procedure, cardiopulmonary resuscitation (CPR), and Glasgow coma score < 9 were significantly associated with pneumonia. In contrast, prior infection and prior antimicrobial use were associated with a protective effect. Presence of subglottic secretion drainage and 15 other variables had no significant effect. Multivariate analysis selected CPR (odds ratio [OR] = 5.13, 95% confidence intervals [CI] = 2.14, 12.26) and continuous sedation (OR = 4.40, 95% CI = 1.83, 10.59) as significant risk factors for pneumonia, while antibiotic use (OR = 0.29, 95% CI = 0.12, 0.69) showed a protective effect. Our findings emphasize that risk factors for pneumonia change during the intubation period, and preventing pneumonia requires a combined approach.




This article has been cited by other articles:


Home page
 Am J Crit CareHome page
R. Garcia, L. Jendresky, L. Colbert, A. Bailey, M. Zaman, and M. Majumder
Reducing Ventilator-Associated Pneumonia Through Advanced Oral-Dental Care: A 48-Month Study
Am. J. Crit. Care., November 1, 2009; 18(6): 523 - 532.
[Abstract] [Full Text] [PDF]

Home page
 Anesth. Analg.Home page
M. Haenggi, H. Ypparila-Wolters, S. Buerki, R. Schlauri, I. Korhonen, J. Takala, and S. M. Jakob
Auditory Event-Related Potentials, Bispectral Index, and Entropy for the Discrimination of Different Levels of Sedation in Intensive Care Unit Patients
Anesth. Analg., September 1, 2009; 109(3): 807 - 816.
[Abstract] [Full Text] [PDF]

Home page
 Am J Crit CareHome page
M. J. Grap
Not-so-Trivial Pursuit: Mechanical Ventilation Risk Reduction
Am. J. Crit. Care., July 1, 2009; 18(4): 299 - 309.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
A. Conway Morris, K. Kefala, T. S. Wilkinson, K. Dhaliwal, L. Farrell, T. Walsh, S. J. Mackenzie, H. Reid, D. J. Davidson, C. Haslett, et al.
C5a Mediates Peripheral Blood Neutrophil Dysfunction in Critically Ill Patients
Am. J. Respir. Crit. Care Med., July 1, 2009; 180(1): 19 - 28.
[Abstract] [Full Text] [PDF]

Home page
 CirculationHome page
R. W. Neumar, J. P. Nolan, C. Adrie, M. Aibiki, R. A. Berg, B. W. Bottiger, C. Callaway, R. S.B. Clark, R. G. Geocadin, E. C. Jauch, et al.
Post-Cardiac Arrest Syndrome: Epidemiology, Pathophysiology, Treatment, and Prognostication A Consensus Statement From the International Liaison Committee on Resuscitation (American Heart Association, Australian and New Zealand Council on Resuscitation, European Resuscitation Council, Heart and Stroke Foundation of Canada, InterAmerican Heart Foundation, Resuscitation Council of Asia, and the Resuscitation Council of Southern Africa); the American Heart Association Emergency Cardiovascular Care Committee; the Council on Cardiovascular Surgery and Anesthesia; the Council on Cardiopulmonary, Perioperative, and Critical Care; the Council on Clinical Cardiology; and the Stroke Council
Circulation, December 2, 2008; 118(23): 2452 - 2483.
[Full Text] [PDF]

Home page
 Eur Respir JHome page
L. Lorente, S. Blot, and J. Rello
Evidence on measures for the prevention of ventilator-associated pneumonia
Eur. Respir. J., December 1, 2007; 30(6): 1193 - 1207.
[Abstract] [Full Text] [PDF]

Home page
 Eur Respir JHome page
S. Nseir, C. Di Pompeo, E. Jozefowicz, B. Cavestri, H. Brisson, M. Nyunga, S. Soubrier, and A. Durocher
Relationship between tracheotomy and ventilator-associated pneumonia: a case control study
Eur. Respir. J., August 1, 2007; 30(2): 314 - 320.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
C. Spies, V. Eggers, G. Szabo, A. Lau, V. von Dossow, H. Schoenfeld, H. Althoff, K. Hegenscheid, B. Bohm, T. Schroeder, et al.
Intervention at the Level of the Neuroendocrine-Immune Axis and Postoperative Pneumonia Rate in Long-term Alcoholics
Am. J. Respir. Crit. Care Med., August 15, 2006; 174(4): 408 - 414.
[Abstract] [Full Text] [PDF]

Home page
 J Intensive Care MedHome page
K. A. Davis
Ventilator-Associated Pneumonia: A Review
J Intensive Care Med, July 1, 2006; 21(4): 211 - 226.
[Abstract] [PDF]

Home page
 CirculationHome page
Part 7.5: Postresuscitation Support
Circulation, December 13, 2005; 112(24_suppl): IV-84 - IV-88.
[Full Text] [PDF]

Home page
 CirculationHome page
Part 4: Advanced Life Support
Circulation, November 29, 2005; 112(22_suppl): III-25 - III-54.
[Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
Guidelines for the Management of Adults with Hospital-acquired, Ventilator-associated, and Healthcare-associated Pneumonia
Am. J. Respir. Crit. Care Med., February 15, 2005; 171(4): 388 - 416.
[Full Text] [PDF]

Home page
 Journal of Pharmacy PracticeHome page
S. A. Voils, K. S. Kim, and E. T. Wittbrodt
Recent Trends in the Management of Ventilator-Associated Pneumonia
Journal of Pharmacy Practice, February 1, 2005; 18(1): 53 - 62.
[Abstract] [PDF]

Home page
 ChestHome page
J. Rello and E. Diaz
Ventilator-Associated Pneumonia, Percutaneous Tracheostomy, and Antimicrobial Prophylaxis
Chest, October 1, 2004; 126(4): 1382 - 1383.
[Full Text] [PDF]

Home page
 J Intensive Care MedHome page
R. M. Mehta and M. S. Niederman
Nosocomial Pneumonia in the Intensive Care Unit: Controversies and Dilemmas
J Intensive Care Med, July 1, 2003; 18(4): 175 - 188.
[Abstract] [PDF]

Home page
 Eur Respir JHome page
S. Nseir, C. Di Pompeo, P. Pronnier, S. Beague, T. Onimus, F. Saulnier, B. Grandbastien, D. Mathieu, M. Delvallez-Roussel, and A. Durocher
Nosocomial tracheobronchitis in mechanically ventilated patients: incidence, aetiology and outcome
Eur. Respir. J., December 1, 2002; 20(6): 1483 - 1489.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
J. Chastre and J.-Y. Fagon
Ventilator-associated Pneumonia
Am. J. Respir. Crit. Care Med., April 1, 2002; 165(7): 867 - 903.
[Abstract] [Full Text] [PDF]

Home page
 ThoraxHome page
S Ewig, T Bauer, and A Torres
The pulmonary physician in critical care * 4: Nosocomial pneumonia
Thorax, April 1, 2002; 57(4): 366 - 371.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
I. M. Ayoub, D. J. Brown, and R. J. Gazmuri
Transtracheal Oxygenation : An Alternative to Endotracheal Intubation During Cardiac Arrest
Chest, November 1, 2001; 120(5): 1663 - 1670.
[Abstract] [Full Text] [PDF]

Home page
 Anesth. Analg.Home page
E. Oschatz, P. Wunderbaldinger, F. Sterz, M. Holzer, J. Kofler, H. Slatin, K. Janata, P. Eisenburger, A. A. Bankier, and A. N. Laggner
Cardiopulmonary Resuscitation Performed by Bystanders Does Not Increase Adverse Effects as Assessed by Chest Radiography
Anesth. Analg., July 1, 2001; 93(1): 128 - 133.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
J. P. Lynch III
Hospital-Acquired Pneumonia : Risk Factors, Microbiology, and Treatment
Chest, February 1, 2001; 119 (2009): 373S - 384S.
[Abstract] [Full Text] [PDF]

Home page
 NEJMHome page
J. E. Heffner
A Wake-Up Call in the Intensive Care Unit
N. Engl. J. Med., May 18, 2000; 342(20): 1520 - 1522.
[Full Text]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Proc. Am. Thorac. Soc. Am. J. Respir. Cell Mol. Biol.
Copyright © 1999 American Thoracic Society 		  CCM abstracts