Am. J. Respir. Crit. Care Med., Vol 152, No. 5, 11 1995, 1697-1701.
Effect of bullectomy on diaphragm strength
JM Travaline, VP Addonizio and GJ Criner
Department of Medicine, Temple University School of Medicine, Philadelphia, PA 19140, USA.
Surgical removal of bullous lesions in selected patients with chronic
obstructive pulmonary disease may significantly improve lung function, gas
exchange, and functional status and reduce dyspnea. Proposed mechanisms by
which bullectomy may produce these beneficial effects include (1) improving
ventilation and perfusion matching by allowing compressed viable lung to
re-expand and participate in gas exchange; (2) restoring outward elastic
tension on small airways, thereby reducing airways obstruction; and (3)
reducing end-expiratory lung volume, thereby diminishing the adverse
effects of chronic hyperinflation on chest wall elastic recoil and
inspiratory muscle force generation. In this report, we demonstrate the
effect of bullectomy on transdiaphragmatic pressure generation, gas
exchange, and exercise capacity in a patient with severe bullous emphysema
who underwent unilateral bullectomy.
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Copyright © 1995 American Thoracic Society
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