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Am. J. Respir. Crit. Care Med., Vol 152, No. 1, 07 1995, 403-407.

Inflammatory effector mechanisms in asthma

JM Drazen, JF Evans, RL Stevens and MA Shipp
Department of Medicine, Brigham and Women's Hospital, Merck Frost Center for Therapeutic Research, Boston, Massachusetts, USA.

Each of these effector systems has the capacity to initiate airway obstruction or alter airway responsiveness in asthma. It is likely that they act in concert in certain asthmatic settings. Further basic and applied research will define their relative roles in asthma.


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Copyright © 1995 American Thoracic Society