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Am. J. Respir. Crit. Care Med., Vol 151, No. 6, Jun 1995, 2033-2036.

Lymphangiomyomatosis recurrence in the allograft after single-lung transplantation

JD O'Brien, JH Lium, JF Parosa, BR Deyoung, MR Wick and EP Trulock
Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.

The evolution of lung transplantation has offered an additional treatment option for patients with a variety of end-stage lung diseases, including some with systemic disorders. Lymphangiomyomatosis (LAM) is a multisystem disease of premenopausal women. The lung is the most frequently involved vital organ, and respiratory failure is the most common case of death. A small number of patients with LAM have undergone lung transplantation. This report describes a case of recurrent LAM in the allograft after single lung transplantation and discusses the implications of this finding.


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