help button home button
AJRCCM
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
This Article
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Huang, L.
Right arrow Articles by Hopewell, P. C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Huang, L.
Right arrow Articles by Hopewell, P. C.

Am. J. Respir. Crit. Care Med., Vol 151, No. 6, Jun 1995, 1866-1871.

Suspected Pneumocystis carinii pneumonia with a negative induced sputum examination. Is early bronchoscopy useful?

L Huang, FM Hecht, JD Stansell, R Montanti, WK Hadley and PC Hopewell
Medicine Service, San Francisco General Hospital Medical Center, California, USA.

In U.S. patients with the acquired immunodeficiency syndrome (AIDS), Pneumocystis carinii pneumonia is the most frequent AIDS-defining opportunistic infection. Sputum induction and bronchoscopy are effective techniques for obtaining specimens used to identify P. carinii although debate continues over their optimal use, specifically whether to perform bronchoscopy after a negative induced sputum examination for P. carinii. To evaluate the usefulness of bronchoscopy in this situation, we reviewed all cases of suspected P. carinii pneumonia in which sputum induction for P. carinii was performed at San Francisco General Hospital during a 4-yr period. Bronchoscopy, performed after a negative induced sputum examination, yielded a diagnosis in 50.5% of evaluations. The most frequent diagnoses were P. carinii pneumonia (192), tracheobronchial Kaposi's sarcoma (93), tuberculosis (28), and Cryptococcus neoformans pneumonia (9). Bronchoscopy provided either the only or an earlier diagnosis in 64.3% of tuberculosis cases. Bronchoscopy with BAL was free of complications, and, importantly, a negative BAL examination for P. carinii allowed physicians to discontinue empiric P. carinii pneumonia treatment in 95%. In patients with suspected P. carinii pneumonia with a negative induced sputum examination for P. carinii, early bronchoscopy with BAL should be performed.


This article has been cited by other articles:


Home page
 ThoraxHome page
J L Davis, D A Welsh, C B Beard, J L Jones, G G Lawrence, M R Fox, K Crothers, A Morris, D Charbonnet, A Swartzman, et al.
Pneumocystis colonisation is common among hospitalised HIV infected patients with non-Pneumocystis pneumonia
Thorax, April 1, 2008; 63(4): 329 - 334.
[Abstract] [Full Text] [PDF]

Home page
 J Intensive Care MedHome page
R. E. Davaro and A. Thirumalai
Life-Threatening Complications of HIV Infection
J Intensive Care Med, March 1, 2007; 22(2): 73 - 81.
[Abstract] [PDF]

Home page
 Proc Am Thorac SocHome page
L. Huang, A. Morris, A. H. Limper, J. M. Beck, and on behalf of the ATS Pneumocystis Workshop Partici
An Official ATS Workshop Summary: Recent Advances and Future Directions in Pneumocystis Pneumonia (PCP)
Proceedings of the ATS, November 1, 2006; 3(8): 655 - 664.
[Abstract] [Full Text] [PDF]

Home page
 Eur Respir JHome page
M. R. Elkins, T. Lane, H. Goldberg, J. Pagliuso, L. A. Garske, E. Hector, L. Marchetto, J. A. Alison, and P. T. P. Bye
Effect of airway clearance techniques on the efficacy of the sputum induction procedure
Eur. Respir. J., November 1, 2005; 26(5): 904 - 908.
[Abstract] [Full Text] [PDF]

Home page
 Eur Respir JHome page
M. Cruciani, P. Marcati, M. Malena, O. Bosco, G. Serpelloni, and C. Mengoli
Meta-analysis of diagnostic procedures for Pneumocystis carinii pneumonia in HIV-1-infected patients
Eur. Respir. J., October 1, 2002; 20(4): 982 - 989.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
A. M. MORRIS, M. SWANSON, H. HA, and L. HUANG
Geographic Distribution of Human Immunodeficiency Virus-associated Pneumocystis carinii Pneumonia in San Francisco
Am. J. Respir. Crit. Care Med., November 1, 2000; 162(5): 1622 - 1626.
[Abstract] [Full Text]

Home page
 Am. J. Respir. Crit. Care Med.Home page
J. RANDALL CURTIS, P. R. YARNOLD, D. N. SCHWARTZ, R. A. WEINSTEIN, and C. L. BENNETT
Improvements in Outcomes of Acute Respiratory Failure for Patients with Human Immunodeficiency Virus-related Pneumocystis carinii Pneumonia
Am. J. Respir. Crit. Care Med., August 1, 2000; 162(2): 393 - 398.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
P. B. Bach, E. A. Calhoun, and C. L. Bennett
The Relation Between Physician Experience and Patterns of Care for Patients With AIDS-Related Pneumocystis carinii Pneumonia: Results From a Survey of 1,500 Physicians in the United States
Chest, June 1, 1999; 115(6): 1563 - 1569.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Respir. Crit. Care Med.Home page
F. SATTLER, L. NICHOLS, L. HIRANO, A. HITI, F. HOFMAN, C. HUGHLETT, L. ZENG, C. T. BOYLEN, and M. KOSS
Nonspecific Interstitial Pneumonitis Mimicking Pneumocystis carinii Pneumonia
Am. J. Respir. Crit. Care Med., September 1, 1997; 156(3): 912 - 917.
[Abstract] [Full Text] [PDF]

Home page
 AIDS Clin CareHome page
Bronchoscopy When Sputum Is PCP-Negative
AIDS Clinical Care, July 1, 1995; 1995(701): 6 - 6.
[Full Text]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Proc. Am. Thorac. Soc. Am. J. Respir. Cell Mol. Biol.
Copyright © 1995 American Thoracic Society