Am. J. Respir. Crit. Care Med., Vol 151, No. 1, Jan 1995, 41-46.
Exposure-response relationship between passive smoking and adult pulmonary function
X Xu and B Li
Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts 02115.
The effects of exposure to environmental tobacco smoke (ETS) on pulmonary
function were investigated in a random sample of 1,033 adults aged 40 to 69
yr from a residential area in Beijing. Compared with those not exposed,
those exposed to ETS either at home or at work were associated with a
102-ml (SE = 40 ml) reduction in FEV1 and a 151-ml (SE = 44 ml) reduction
in FVC after adjustment for confounding factors. Home and work ETS exposure
was respectively associated with a 102-ml (SE = 33 ml) and 61-ml (SE = 34
ml) reduction in FEV1. When the subjects were grouped into three exposure
categories (none, home only or work only, and both), the deficits in FEV1
and FVC in the third category were the greatest and statistically
significant. The adverse effects of ETS were consistently observed in
stratified analyses according to sex, occupational exposure, indoor use of
coal stoves, and education. When ETS exposure was measured by the
cigarettes smoked by other household members at home per day, an
exposure-response association with FEV1 and FVC was again statistically
significant. In conclusion, this study demonstrated that there is a
significant association between exposure to ETS and reduced levels of FEV1
and FVC in adults, and such an association is dose-dependent.
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Copyright © 1995 American Thoracic Society
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