Am. J. Respir. Crit. Care Med., Vol 150, No. 2, Aug 1994, 408-414.
Acute pulmonary response of asthmatics to aerosols and gases generated by airbag deployment [published erratum appears in Am J Respir Crit Care Med 1994 Oct;150(4):1205]
KB Gross, AH Haidar, MA Basha, TL Chan, CJ Gwizdala, RG Wooley, J Popovich Jr and CJ] Cwizdala CJ [corrected to Gwizdala
Department of Automotive Safety and Health Research, General Motors Research and Development Center, Warren, Michigan.
The purpose of this study was to determine whether the aerosols and gases
that vent into an automobile's passenger compartment after airbag
deployment pose a risk to the asthmatic population. After baseline
pulmonary function measurements were taken, 24 diagnosed asthmatic subjects
were placed in the rear seat of an automobile, and a driver- passenger
airbag system was deployed. Subjects remained in the vehicle with the
windows closed and no ventilation for 20 min or until they perceived or
demonstrated signs of chest tightness and bronchoconstriction. They then
exited the vehicle and were retested immediately after exposure and 2 and 4
h after exposure. Ten of the 24 subjects demonstrated clinically
significant bronchoconstrictive episodes, three of which required medical
intervention. These three events were quickly reversed by beta-agonist
therapy. When eight of the responding subjects were reexposed at later
dates to the same supplemental inflatable restraints emissions while
wearing a high- efficiency particulate absolute respirator, which prevented
inhalation of the particles but allowed passage of the gases, the pulmonary
response was essentially eliminated. We conclude that the aerosols
generated by deployment of automotive driver-passenger airbag systems can
induce significant asthmatic reactions in some individuals.